6-[4-(2,4-dihydroxy-3,3-dimethylbutyrylamino)-3,5-dimethylphenoxy]-2,2-dimethylhexanoic acid ethyl ester

Base Information

Chemical Name:6-[4-(2,4-dihydroxy-3,3-dimethylbutyrylamino)-3,5-dimethylphenoxy]-2,2-dimethylhexanoic acid ethyl ester
CAS No.:616236-30-7
Molecular Formula:C₂₄H₃₉NO₆
Molecular Weight:437.577
Hs Code.:

Synonyms:6-[4-(2,4-dihydroxy-3,3-dimethylbutyrylamino)-3,5-dimethylphenoxy]-2,2-dimethylhexanoic acid ethyl ester

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Chemical Property of 6-[4-(2,4-dihydroxy-3,3-dimethylbutyrylamino)-3,5-dimethylphenoxy]-2,2-dimethylhexanoic acid ethyl ester

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Technology Process of 6-[4-(2,4-dihydroxy-3,3-dimethylbutyrylamino)-3,5-dimethylphenoxy]-2,2-dimethylhexanoic acid ethyl ester

There total 6 articles about 6-[4-(2,4-dihydroxy-3,3-dimethylbutyrylamino)-3,5-dimethylphenoxy]-2,2-dimethylhexanoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 616236-29-4
6-{4-[2-(1-ethoxyethoxy)-4-hydroxy-3,3-dimethylbutyrylamino]-3,5-dimethylphenoxy}-2,2-dimethylhexanoic acid ethyl ester

: 616236-30-7
6-[4-(2,4-dihydroxy-3,3-dimethylbutyrylamino)-3,5-dimethylphenoxy]-2,2-dimethylhexanoic acid ethyl ester

Guidance literature:: With acetic acid; In water; for 4h;
DOI:10.1080/00397910500377545

Reference yield:

: 3-(1-ethoxy-ethoxy)-4,4-dimethyl-dihydro-furan-2-one

: 616236-30-7
6-[4-(2,4-dihydroxy-3,3-dimethylbutyrylamino)-3,5-dimethylphenoxy]-2,2-dimethylhexanoic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 39 percent / NaH / dimethylformamide / 6 h

2: 76 percent / HOAc / H₂O / 4 h

With sodium hydride; acetic acid; In water; N,N-dimethyl-formamide;
DOI:10.1080/00397910500377545

Reference yield:

: 616236-28-3
6-(4-amino-3,5-dimethylphenoxy)-2,2-dimethylhexanoic acid ethyl ester

: 616236-30-7
6-[4-(2,4-dihydroxy-3,3-dimethylbutyrylamino)-3,5-dimethylphenoxy]-2,2-dimethylhexanoic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 39 percent / NaH / dimethylformamide / 6 h

2: 76 percent / HOAc / H₂O / 4 h

With sodium hydride; acetic acid; In water; N,N-dimethyl-formamide;
DOI:10.1080/00397910500377545