tert-butyl (3-((5-bromo-2-chloropyrimidin-4-yl)amino)phenyl)carbamate

Base Information

Chemical Name:tert-butyl (3-((5-bromo-2-chloropyrimidin-4-yl)amino)phenyl)carbamate
CAS No.:1202760-30-2
Molecular Formula:C₁₅H₁₆BrClN₄O₂
Molecular Weight:399.675
Hs Code.:

Synonyms:tert-butyl (3-((5-bromo-2-chloropyrimidin-4-yl)amino)phenyl)carbamate

Suppliers and Price of tert-butyl (3-((5-bromo-2-chloropyrimidin-4-yl)amino)phenyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl (3-((5-bromo-2-chloropyrimidin-4-yl)amino)phenyl)carbamate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of tert-butyl (3-((5-bromo-2-chloropyrimidin-4-yl)amino)phenyl)carbamate

There total 2 articles about tert-butyl (3-((5-bromo-2-chloropyrimidin-4-yl)amino)phenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 36082-50-5
2,4-dichloro-5-bromopyrimidine

: 68621-88-5
(3-aminophenyl)carbamic acid tert-butyl ester

: 1202760-30-2
tert-butyl (3-((5-bromo-2-chloropyrimidin-4-yl)amino)phenyl)carbamate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2016.12.006

Reference yield:

: 1202760-30-2
tert-butyl (3-((5-bromo-2-chloropyrimidin-4-yl)amino)phenyl)carbamate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In butan-1-ol; at 0 - 20 ℃; for 5h;

Reference yield: 52.0%

: 107-93-7
(E)-but-2-enoic acid

: 1202760-30-2
tert-butyl (3-((5-bromo-2-chloropyrimidin-4-yl)amino)phenyl)carbamate

: tert-butyl (3-(2-chloro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl)-phenyl)carbamate

Guidance literature:: (E)-but-2-enoic acid; tert-butyl (3-((5-bromo-2-chloropyrimidin-4-yl)amino)phenyl)carbamate; With bis(benzonitrile)palladium(II) dichloride; N-ethyl-N,N-diisopropylamine; tris-(o-tolyl)phosphine; In toluene; at 65 ℃; for 6h; Inert atmosphere;

With acetic anhydride; In toluene; for 1.5h;