C₂₆H₄₅IO₃Si

Base Information

• Chemical Name: C₂₆H₄₅IO₃Si
• CAS No.: 1569075-97-3
• Molecular Formula: C₂₆H₄₅IO₃Si
• Molecular Weight: 560.632
• Mol file: 1569075-97-3.mol

Synonyms:C₂₆H₄₅IO₃Si

Chemical Property of C₂₆H₄₅IO₃Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₄₅IO₃Si

There total 6 articles about C₂₆H₄₅IO₃Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C26H49IO3Si (1569075-96-2) → C26H45IO3Si (1569075-97-3)

Guidance literature:

With Dess-Martin periodane; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.tetlet.2014.01.071

Reference yield:

ethyl 2-{(1S,2R,5S,6S)-2-[(E)-6-iodo-3-oxohepta-1,6-dien-1-yl]-2,6-dimethyl-5-triisopropylsilyloxycyclohexyl}acetate (1569075-95-1) → C26H45IO3Si (1569075-97-3)

Guidance literature:

Multi-step reaction with 2 steps

1: diisobutylaluminium hydride / dichloromethane / 0 °C / Inert atmosphere

2: Dess-Martin periodane / dichloromethane / 20 °C / Inert atmosphere

With diisobutylaluminium hydride; Dess-Martin periodane; In dichloromethane;

DOI:10.1016/j.tetlet.2014.01.071

Reference yield:

ethyl 2-((1S,2S,5S,6S)-2-formyl-2,6-dimethyl-5-((triisopropylsilyl)oxy)cyclohexyl)acetate (1569075-93-9) → C26H45IO3Si (1569075-97-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydride / 1,4-dioxane / 0.17 h / 20 °C / Inert atmosphere

1.2: 3 h / 110 °C / Inert atmosphere

2.1: diisobutylaluminium hydride / dichloromethane / 0 °C / Inert atmosphere

3.1: Dess-Martin periodane / dichloromethane / 20 °C / Inert atmosphere

With sodium hydride; diisobutylaluminium hydride; Dess-Martin periodane; In 1,4-dioxane; dichloromethane; 1.1: |Horner-Wadsworth-Emmons Olefination / 1.2: |Horner-Wadsworth-Emmons Olefination;

DOI:10.1016/j.tetlet.2014.01.071

upstream raw materials:

ethyl 2-((1S,2S,5S,6S)-2-formyl-2,6-dimethyl-5-((triisopropylsilyl)oxy)cyclohexyl)acetate

dimethyl (5-iodo-2-oxohex-5-en-1-yl)phosphonate

ethyl 2-{(1S,2R,5S,6S)-2-[(E)-6-iodo-3-oxohepta-1,6-dien-1-yl]-2,6-dimethyl-5-triisopropylsilyloxycyclohexyl}acetate

C₂₆H₄₉IO₃Si