(+/-)-α-(2-chlorophenyl)-α-<2-<(1-methylethyl)(phenylmethyl)amino>ethyl>-1-piperidinebutanamide

Base Information

Chemical Name:(+/-)-α-(2-chlorophenyl)-α-<2-<(1-methylethyl)(phenylmethyl)amino>ethyl>-1-piperidinebutanamide
CAS No.:116078-63-8
Molecular Formula:C₂₇H₃₈ClN₃O
Molecular Weight:456.071
Hs Code.:

Synonyms:(+/-)-α-(2-chlorophenyl)-α-<2-<(1-methylethyl)(phenylmethyl)amino>ethyl>-1-piperidinebutanamide

Suppliers and Price of (+/-)-α-(2-chlorophenyl)-α-<2-<(1-methylethyl)(phenylmethyl)amino>ethyl>-1-piperidinebutanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (+/-)-α-(2-chlorophenyl)-α-<2-<(1-methylethyl)(phenylmethyl)amino>ethyl>-1-piperidinebutanamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+/-)-α-(2-chlorophenyl)-α-<2-<(1-methylethyl)(phenylmethyl)amino>ethyl>-1-piperidinebutanamide

There total 4 articles about (+/-)-α-(2-chlorophenyl)-α-<2-<(1-methylethyl)(phenylmethyl)amino>ethyl>-1-piperidinebutanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 116078-62-7
(+/-)-α-(2-chlorophenyl)-α-<2-<(1-methylethyl)(phenylmethyl)amino>ethyl>-1-piperidinebutanenitrile

: 116078-63-8
(+/-)-α-(2-chlorophenyl)-α-<2-<(1-methylethyl)(phenylmethyl)amino>ethyl>-1-piperidinebutanamide

Guidance literature:: With sulfuric acid; at 95 - 100 ℃; for 2.5h;
DOI:10.1021/jm00119a017

Reference yield:

: 1932-03-2
2-(piperidin-4-yl)ethyl chloride

: 116078-63-8
(+/-)-α-(2-chlorophenyl)-α-<2-<(1-methylethyl)(phenylmethyl)amino>ethyl>-1-piperidinebutanamide

Guidance literature:: Multi-step reaction with 3 steps

1: 38 percent / sodamide / toluene / 1.5 h / 80 °C

2: NaNH₂ / toluene / 2 h / 90 °C

3: 87 percent / conc. H₂SO₄ / 2.5 h / 95 - 100 °C

With sulfuric acid; sodium amide; In toluene;
DOI:10.1021/jm00119a017

Reference yield:

: 2856-63-5
2-Chlorophenylacetonitrile

: 116078-63-8
(+/-)-α-(2-chlorophenyl)-α-<2-<(1-methylethyl)(phenylmethyl)amino>ethyl>-1-piperidinebutanamide

Guidance literature:: Multi-step reaction with 3 steps

1: 38 percent / sodamide / toluene / 1.5 h / 80 °C

2: NaNH₂ / toluene / 2 h / 90 °C

3: 87 percent / conc. H₂SO₄ / 2.5 h / 95 - 100 °C

With sulfuric acid; sodium amide; In toluene;
DOI:10.1021/jm00119a017