1L-(1,3/2,4)-1-O-Acetyl-2,3,4-tri-O-benzyl-5-C-hydroxymethyl-5-cyclohexen-1,2,3,4-tetrol

Base Information

• Chemical Name: 1L-(1,3/2,4)-1-O-Acetyl-2,3,4-tri-O-benzyl-5-C-hydroxymethyl-5-cyclohexen-1,2,3,4-tetrol
• CAS No.: 104976-59-2
• Molecular Formula: C₃₀H₃₂O₆
• Molecular Weight: 488.58
• Mol file: 104976-59-2.mol

Synonyms:1L-(1,3/2,4)-1-O-Acetyl-2,3,4-tri-O-benzyl-5-C-hydroxymethyl-5-cyclohexen-1,2,3,4-tetrol

Chemical Property of 1L-(1,3/2,4)-1-O-Acetyl-2,3,4-tri-O-benzyl-5-C-hydroxymethyl-5-cyclohexen-1,2,3,4-tetrol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1L-(1,3/2,4)-1-O-Acetyl-2,3,4-tri-O-benzyl-5-C-hydroxymethyl-5-cyclohexen-1,2,3,4-tetrol

There total 3 articles about 1L-(1,3/2,4)-1-O-Acetyl-2,3,4-tri-O-benzyl-5-C-hydroxymethyl-5-cyclohexen-1,2,3,4-tetrol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1L-(1,3/2,4)-1-O-Acetyl-2,3,4-tri-O-benzyl-5-C-<(tert-butyldiphenylsilyloxy)methyl>-5-cyclohexen-1,2,3,4-tetrol (104976-77-4) → 1L-(1,3/2,4)-1-O-Acetyl-2,3,4-tri-O-benzyl-5-C-hydroxymethyl-5-cyclohexen-1,2,3,4-tetrol (104976-59-2)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 1h; Ambient temperature;

Reference yield:

2D-(2,4/3)-2,3,4-Tri-O-benzyl-5-C-<(tert-butyldiphenylsilyloxy)methyl>-2,3,4-trihydroxy-5-cyclohexen-1-on (104976-75-2) → 1L-(1,3/2,4)-1-O-Acetyl-2,3,4-tri-O-benzyl-5-C-hydroxymethyl-5-cyclohexen-1,2,3,4-tetrol (104976-59-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 52 percent / NaBH₄ / ethanol / 12 h / Ambient temperature

2: 95 percent / Py / 12 h

3: 70 percent / Bu₄NF*3H₂O / tetrahydrofuran / 1 h / Ambient temperature

With pyridine; sodium tetrahydroborate; tetrabutyl ammonium fluoride; In tetrahydrofuran; ethanol;

Reference yield:

1L-(1,3/2,4)-2,3,4-Tri-O-benzyl-5-C-<(tert-butyldiphenylsilyloxy)methyl>-5-cyclohexen-1,2,3,4-tetrol (105017-71-8) → 1L-(1,3/2,4)-1-O-Acetyl-2,3,4-tri-O-benzyl-5-C-hydroxymethyl-5-cyclohexen-1,2,3,4-tetrol (104976-59-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / Py / 12 h

2: 70 percent / Bu₄NF*3H₂O / tetrahydrofuran / 1 h / Ambient temperature

With pyridine; tetrabutyl ammonium fluoride; In tetrahydrofuran;

upstream raw materials:

1L-(1,3/2,4)-1-O-Acetyl-2,3,4-tri-O-benzyl-5-C-<(tert-butyldiphenylsilyloxy)methyl>-5-cyclohexen-1,2,3,4-tetrol

2D-(2,4/3)-2,3,4-Tri-O-benzyl-5-C-<(tert-butyldiphenylsilyloxy)methyl>-2,3,4-trihydroxy-5-cyclohexen-1-on

1L-(1,3/2,4)-2,3,4-Tri-O-benzyl-5-C-<(tert-butyldiphenylsilyloxy)methyl>-5-cyclohexen-1,2,3,4-tetrol

Downstream raw materials:

1L-(1,3,5/2,4)-2,3,4-Tri-O-benzyl-5-C-hydroxymethyl-1,2,3,4-cyclohexantetrol

1L-(1,2,4/3,5)-2,3,4-Tri-O-benzyl-1-C-hydroxymethyl-2,3,4,5-cyclohexantetrol

(1R,2R,3S,4R,5R)-3,4-Bis-benzyloxy-2-[(1R,4R,5S,6S)-4,5,6-tris-benzyloxy-3-(2-methoxy-ethoxymethoxymethyl)-cyclohex-2-enyloxy]-6,8-dioxa-bicyclo[3.2.1]octane

[(1R,2R,3S,4S,5R)-2,3,4-Tris-benzyloxy-5-((1R,2R,3S,4R,5R)-3,4-bis-benzyloxy-6,8-dioxa-bicyclo[3.2.1]oct-2-yloxy)-cyclohexyl]-methanol