tert-butyl (3aS,10aS)-9-{(S)-2-[4-(2,6-dichlorobenzyloxy)-phenyl]-1-methoxycarbonylethyl}-10-oxo-3,3a,4,7,8,9,10,10a-octahydropyrrolo[2,3-c]azonine-1(2H)-carboxylate

Base Information

• Chemical Name: tert-butyl (3aS,10aS)-9-{(S)-2-[4-(2,6-dichlorobenzyloxy)-phenyl]-1-methoxycarbonylethyl}-10-oxo-3,3a,4,7,8,9,10,10a-octahydropyrrolo[2,3-c]azonine-1(2H)-carboxylate
• CAS No.: 1000049-77-3
• Molecular Formula: C₃₂H₃₈Cl₂N₂O₆
• Molecular Weight: 617.57
• Mol file: 1000049-77-3.mol

Synonyms:tert-butyl (3aS,10aS)-9-{(S)-2-[4-(2,6-dichlorobenzyloxy)-phenyl]-1-methoxycarbonylethyl}-10-oxo-3,3a,4,7,8,9,10,10a-octahydropyrrolo[2,3-c]azonine-1(2H)-carboxylate

Chemical Property of tert-butyl (3aS,10aS)-9-{(S)-2-[4-(2,6-dichlorobenzyloxy)-phenyl]-1-methoxycarbonylethyl}-10-oxo-3,3a,4,7,8,9,10,10a-octahydropyrrolo[2,3-c]azonine-1(2H)-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl (3aS,10aS)-9-{(S)-2-[4-(2,6-dichlorobenzyloxy)-phenyl]-1-methoxycarbonylethyl}-10-oxo-3,3a,4,7,8,9,10,10a-octahydropyrrolo[2,3-c]azonine-1(2H)-carboxylate

There total 1 articles about tert-butyl (3aS,10aS)-9-{(S)-2-[4-(2,6-dichlorobenzyloxy)-phenyl]-1-methoxycarbonylethyl}-10-oxo-3,3a,4,7,8,9,10,10a-octahydropyrrolo[2,3-c]azonine-1(2H)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C27H30Cl2N2O4 + di-tert-butyl dicarbonate (24424-99-5) → tert-butyl (3aS,10aS)-9-{(S)-2-[4-(2,6-dichlorobenzyloxy)-phenyl]-1-methoxycarbonylethyl}-10-oxo-3,3a,4,7,8,9,10,10a-octahydropyrrolo[2,3-c]azonine-1(2H)-carboxylate (1000049-77-3)

Guidance literature:

In dichloromethane; at 20 ℃; for 20h;

DOI:10.1021/jo701703e

Reference yield: 100.0%

tert-butyl (3aS,10aS)-9-{(S)-2-[4-(2,6-dichlorobenzyloxy)-phenyl]-1-methoxycarbonylethyl}-10-oxo-3,3a,4,7,8,9,10,10a-octahydropyrrolo[2,3-c]azonine-1(2H)-carboxylate (1000049-77-3) → C31H36Cl2N2O6 (1000049-79-5)

Guidance literature:

In tetrahydrofuran; methanol; sodium hydroxide; at 0 ℃; for 3h;

DOI:10.1021/jo701703e

Reference yield: 95.0%

tert-butyl (3aS,10aS)-9-{(S)-2-[4-(2,6-dichlorobenzyloxy)-phenyl]-1-methoxycarbonylethyl}-10-oxo-3,3a,4,7,8,9,10,10a-octahydropyrrolo[2,3-c]azonine-1(2H)-carboxylate (1000049-77-3) + methylamine (74-89-5) → C32H39Cl2N3O5

Guidance literature:

In ethanol; at 20 ℃; for 36h;

DOI:10.1021/jo701703e

upstream raw materials:

di-tert-butyl dicarbonate

Downstream raw materials:

C₃₁H₃₆Cl₂N₂O₆