(S)-2-[BENZYL-(3-CHLORO-2-HYDROXY-PROPYL)-AMINO]-N-(4-BENZYLOXY-PHENYL)-ACETAMIDE

Base Information

Chemical Name:(S)-2-[BENZYL-(3-CHLORO-2-HYDROXY-PROPYL)-AMINO]-N-(4-BENZYLOXY-PHENYL)-ACETAMIDE
CAS No.:777934-41-5
Molecular Formula:C25H27 Cl N2 O3
Molecular Weight:438.954
Hs Code.:2924299090
Mol file:777934-41-5.mol

Synonyms:2-[Benzyl((2S)-3-chloro-2-hydroxypropyl)amino]-N-(4-benzyloxyphenyl)acetamide

Suppliers and Price of (S)-2-[BENZYL-(3-CHLORO-2-HYDROXY-PROPYL)-AMINO]-N-(4-BENZYLOXY-PHENYL)-ACETAMIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-2-(Benzyl(3-chloro-2-hydroxypropyl)amino)-N-(4-(benzyloxy)phenyl)acetamide 97%
1g
$ 708.00

American Custom Chemicals Corporation
(S)-2-[BENZYL-(3-CHLORO-2-HYDROXY-PROPYL)-AMINO]-N-(4-BENZYLOXY-PHENYL)-ACETAMIDE 95.00%
500MG
$ 970.20

Total 3 raw suppliers

Chemical Property of (S)-2-[BENZYL-(3-CHLORO-2-HYDROXY-PROPYL)-AMINO]-N-(4-BENZYLOXY-PHENYL)-ACETAMIDE

Chemical Property:

Vapor Pressure:1.04E-17mmHg at 25°C
Refractive Index:1.63
Boiling Point:648.6°C at 760 mmHg
Flash Point:346.1°C
PSA：61.80000
Density:1.252g/cm³
LogP:4.37900

Purity/Quality:

97% ^*data from raw suppliers

(S)-2-(Benzyl(3-chloro-2-hydroxypropyl)amino)-N-(4-(benzyloxy)phenyl)acetamide 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-2-[BENZYL-(3-CHLORO-2-HYDROXY-PROPYL)-AMINO]-N-(4-BENZYLOXY-PHENYL)-ACETAMIDE

There total 3 articles about (S)-2-[BENZYL-(3-CHLORO-2-HYDROXY-PROPYL)-AMINO]-N-(4-BENZYLOXY-PHENYL)-ACETAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 67843-74-7,24969-06-0,13403-37-7
(S)-epichlorohydrin

: 777934-39-1
2-benzylamino-N-(4-benzyloxyphenyl)acetamide

: 777934-41-5
2-{benzyl[(2S)-3-chloro-2-hydroxypropyl]amino}-N-(4-benzyloxyphenyl)acetamide

Guidance literature:: With magnesium sulfate; In methanol; dichloromethane; at 35 ℃; for 72h;

Reference yield:

: 19514-92-2
N-[4-(benzyloxy)phenyl]-2-chloroacetamide

: 777934-41-5
2-{benzyl[(2S)-3-chloro-2-hydroxypropyl]amino}-N-(4-benzyloxyphenyl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / tetrahydrofuran / 18 h / Heating

2: MgSO₄ / methanol; CH₂Cl₂ / 72 h / 35 °C

With magnesium sulfate; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/ol048235t

Reference yield:

: 51388-20-6
4-benzyloxyaniline hydrochloride

: 777934-41-5
2-{benzyl[(2S)-3-chloro-2-hydroxypropyl]amino}-N-(4-benzyloxyphenyl)acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / K₂CO₃ / tetrahydrofuran / 6 h / 20 °C

2: 93 percent / tetrahydrofuran / 18 h / Heating

3: MgSO₄ / methanol; CH₂Cl₂ / 72 h / 35 °C

With magnesium sulfate; potassium carbonate; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/ol048235t