9-hydroxy-6-(4-hydroxyphenyl)-2,2-diphenyl-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one

Base Information

• Chemical Name: 9-hydroxy-6-(4-hydroxyphenyl)-2,2-diphenyl-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one
• CAS No.: 1105056-24-3
• Molecular Formula: C₂₈H₁₈O₆
• Molecular Weight: 450.447
• Mol file: 1105056-24-3.mol

Synonyms:9-hydroxy-6-(4-hydroxyphenyl)-2,2-diphenyl-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one

Chemical Property of 9-hydroxy-6-(4-hydroxyphenyl)-2,2-diphenyl-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9-hydroxy-6-(4-hydroxyphenyl)-2,2-diphenyl-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one

There total 2 articles about 9-hydroxy-6-(4-hydroxyphenyl)-2,2-diphenyl-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.6%

Dichlorodiphenylmethane (2051-90-3) + scutellarein (529-53-3) → 9-hydroxy-6-(4-hydroxyphenyl)-2,2-diphenyl-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one (1105056-24-3)

Guidance literature:

In diphenylether; at 175 ℃; for 0.5h; Inert atmosphere;

DOI:10.2174/15701786113109990046

Reference yield:

scutellarin (27740-01-8,676536-34-8) → 9-hydroxy-6-(4-hydroxyphenyl)-2,2-diphenyl-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one (1105056-24-3)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / ethanol; water / 36 h / Inert atmosphere; Reflux

2: diphenylether / 0.5 h / 175 °C / Inert atmosphere

With hydrogenchloride; In diphenylether; ethanol; water;

DOI:10.2174/15701786113109990046

Reference yield: 94.0%

N-(2-chlorethyl)morpholine (3240-94-6) + 9-hydroxy-6-(4-hydroxyphenyl)-2,2-diphenyl-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one (1105056-24-3) → C34H29NO7 (1436402-36-6)

Guidance literature:

With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 25 ℃; for 6h; Inert atmosphere;

DOI:10.2174/1570178611666140421230118

upstream raw materials:

Dichlorodiphenylmethane

scutellarein

scutellarin

Downstream raw materials:

9-hydroxy-2,2-diphenyl-6-[4-(phenylmethoxy)phenyl]-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one

hispidulin

5,6,7-trihydroxy-2-[4-(phenylmethoxy)phenyl]-4H-1-benzopyran-4-one

7-(benzyloxy)-2-(4-(benzyloxy)phenyl)-5,6-dihydroxy-4H-chromen-4-one