2,2'-(2-cyclohexylethane-1,1-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane)

Base Information

• Chemical Name: 2,2'-(2-cyclohexylethane-1,1-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane)
• CAS No.: 1227056-27-0
• Molecular Formula: C₂₀H₃₈B₂O₄
• Molecular Weight: 364.141
• Mol file: 1227056-27-0.mol

Synonyms:2,2'-(2-cyclohexylethane-1,1-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane)

Chemical Property of 2,2'-(2-cyclohexylethane-1,1-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2'-(2-cyclohexylethane-1,1-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane)

There total 10 articles about 2,2'-(2-cyclohexylethane-1,1-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

2-cyclohexylacetylene (931-48-6) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 2,2'-(2-cyclohexylethane-1,1-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) (1227056-27-0)

Guidance literature:

With potassium tert-butylate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; copper(l) chloride; In toluene; at 23 ℃; for 15h; regioselective reaction;

DOI:10.1039/c9sc00378a

Reference yield: 65.0%

ethylidenecyclohexane (1003-64-1) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 2,2'-(2-cyclohexylethane-1,1-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) (1227056-27-0)

Guidance literature:

With zirconocene dichloride; lithium methanolate; In toluene; at 100 ℃; for 8h; under 760.051 Torr; Inert atmosphere;

Reference yield: 62.0%

cyclohexylmethyl iodide (5469-33-0) + carbon monoxide (201230-82-2) + bis(pinacol)diborane (73183-34-3) → 2,2'-(2-cyclohexylethane-1,1-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) (1227056-27-0)

Guidance literature:

With diethoxymethylane; sodium ethanolate; copper(l) chloride; In 1,4-dioxane; at 100 ℃; for 16h; under 7500.75 Torr; Autoclave;

DOI:10.1002/anie.202102197

upstream raw materials:

2-cyclohexylacetylene

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

4,4,5,5-tetramethyl-2-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl]-1,3,2-dioxaborolane

cyclohexanecarbaldehyde

Downstream raw materials:

(E)-2-(4',4',5',5'-tetramethyl-1',3',2'-dioxaborolan-2'-yl)-1-cyclohexyl-3-phenylbut-2-ene

2-cyclohexyl-1-(pyridin-2-yl)ethan-1-one