C₁₆H₂₀N₄O

Base Information

• Chemical Name: C₁₆H₂₀N₄O
• CAS No.: 1171114-58-1
• Molecular Formula: C₁₆H₂₀N₄O
• Molecular Weight: 284.361
• Mol file: 1171114-58-1.mol

Synonyms:C₁₆H₂₀N₄O

Chemical Property of C₁₆H₂₀N₄O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₂₀N₄O

There total 7 articles about C₁₆H₂₀N₄O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

hexamethylene imine (111-49-9) + 5-methyl-2-(2H-1,2,3-triazol-2-yl)-benzonitrile → C16H20N4O (1171114-58-1)

Guidance literature:

hexamethylene imine; With ethylmagnesium bromide; In tetrahydrofuran; diethyl ether; at 20 ℃; for 1.5h;

5-methyl-2-(2H-1,2,3-triazol-2-yl)-benzonitrile; In tetrahydrofuran; at 20 ℃; for 0.5h; Solvent; Reagent/catalyst; Temperature;

Reference yield:

2-(4-methylphenyl)-2H-[1,2,3]-triazole (103755-53-9) → C16H20N4O (1171114-58-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: tert.-butyl lithium / diethyl ether; pentane / 1 h / -80 °C

1.2: 2 h / -50 °C

2.1: copper diacetate; Triphenylphosphine oxide; silver(l) oxide / acetonitrile / 120 °C

3.1: ethylmagnesium bromide / tetrahydrofuran; diethyl ether / 1.5 h / 20 °C

3.2: 0.5 h / 20 °C

With ethylmagnesium bromide; tert.-butyl lithium; copper diacetate; Triphenylphosphine oxide; silver(l) oxide; In tetrahydrofuran; diethyl ether; acetonitrile; pentane;

Reference yield:

glyoxal-bis-p-tolylhydrazone (79762-67-7) → C16H20N4O (1171114-58-1)

Guidance literature:

Multi-step reaction with 4 steps

1.1: copper(II) bis(trifluoromethanesulfonate) / toluene / 4 h / Reflux

2.1: tert.-butyl lithium / diethyl ether; pentane / 1 h / -80 °C

2.2: 2 h / -50 °C

3.1: copper diacetate; Triphenylphosphine oxide; silver(l) oxide / acetonitrile / 120 °C

4.1: ethylmagnesium bromide / tetrahydrofuran; diethyl ether / 1.5 h / 20 °C

4.2: 0.5 h / 20 °C

With ethylmagnesium bromide; tert.-butyl lithium; copper diacetate; copper(II) bis(trifluoromethanesulfonate); Triphenylphosphine oxide; silver(l) oxide; In tetrahydrofuran; diethyl ether; toluene; acetonitrile; pentane;

upstream raw materials:

2-(2H-1,2,3-triazol-2-yl)-5-methylbenzoic acid

2-(2-iodo-4-methylphenyl)-2H-[1,2,3]triazole

hexamethylene imine

glyoxal-bis-p-tolylhydrazone