1-(2-BROMOETHYL)PYRROLE

Base Information

• Chemical Name: 1-(2-BROMOETHYL)PYRROLE
• CAS No.: 78358-86-8
• Molecular Formula: C₆H₈BrN
• Molecular Weight: 174.04
• Hs Code.: 2933990090
• Mol file: 78358-86-8.mol

Synonyms:-(2-Bromoethyl)pyrrole;

Chemical Property of 1-(2-BROMOETHYL)PYRROLE

Chemical Property:

• Vapor Pressure: 0.402mmHg at 25°C
• Refractive Index: 1.546
• Boiling Point: 203.108 °C at 760 mmHg
• Flash Point: 76.638 °C
• PSA: 4.93000
• Density: 1.408 g/cm³
• LogP: 1.88300
• Storage Temp.: Refrigerator

Purity/Quality:

98% ^*data from raw suppliers

1-(2-Bromoethyl)pyrrole ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38-41-37/38
• Safety Statements: 26-36/37/39-39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(2-BROMOETHYL)PYRROLE

There total 2 articles about 1-(2-BROMOETHYL)PYRROLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cis,trans-2,5-dimethoxytetrahydrofuran (696-59-3) + 2-bromoethylamine (107-09-5) → N-(2-bromoethyl)pyrrole (78358-86-8)

Guidance literature:

With sodium acetate; acetic acid; at 115 - 117 ℃; Inert atmosphere;

Reference yield:

2-bromoethylamine hydrobromide (2576-47-8) + 2,5-dimethoxytetrahydrofuran (34160-24-2) → N-(2-bromoethyl)pyrrole (78358-86-8)

Guidance literature:

With sodium acetate; acetic acid; at 115 - 117 ℃;

Reference yield:

N-(2-bromoethyl)pyrrole (78358-86-8) → C18H18N2O3

Guidance literature:

Multi-step reaction with 2 steps

1: sodium ethanolate / ethanol / 0.67 h / 40 - 85 °C

2: 5,5-dimethyl-1,3-cyclohexadiene / 150 - 155 °C

With sodium ethanolate; In 5,5-dimethyl-1,3-cyclohexadiene; ethanol;

upstream raw materials:

cis,trans-2,5-dimethoxytetrahydrofuran

2-bromoethylamine

2-bromoethylamine hydrobromide

2,5-dimethoxytetrahydrofuran

Refernces

• 1、 -. "COMPOSITIONS AND METHODS FOR THE TREATMENT OF MODERATE TO SEVERE PAIN". Paragraph 00110-00112. . Retrieved 2013/12/03.