methyl (2S,5S)-2-(4-allyloxybenzyl)-3-aza-9-(tert-butoxycarbonylamino)-5-(9H-9-fluorenylmethyloxycarbonylamino)-4-oxononanoate

Base Information

• Chemical Name: methyl (2S,5S)-2-(4-allyloxybenzyl)-3-aza-9-(tert-butoxycarbonylamino)-5-(9H-9-fluorenylmethyloxycarbonylamino)-4-oxononanoate
• CAS No.: 900521-37-1
• Molecular Formula: C₃₉H₄₇N₃O₈
• Molecular Weight: 685.817
• Mol file: 900521-37-1.mol

Synonyms:methyl (2S,5S)-2-(4-allyloxybenzyl)-3-aza-9-(tert-butoxycarbonylamino)-5-(9H-9-fluorenylmethyloxycarbonylamino)-4-oxononanoate

Chemical Property of methyl (2S,5S)-2-(4-allyloxybenzyl)-3-aza-9-(tert-butoxycarbonylamino)-5-(9H-9-fluorenylmethyloxycarbonylamino)-4-oxononanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl (2S,5S)-2-(4-allyloxybenzyl)-3-aza-9-(tert-butoxycarbonylamino)-5-(9H-9-fluorenylmethyloxycarbonylamino)-4-oxononanoate

There total 2 articles about methyl (2S,5S)-2-(4-allyloxybenzyl)-3-aza-9-(tert-butoxycarbonylamino)-5-(9H-9-fluorenylmethyloxycarbonylamino)-4-oxononanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

methyl (2S)-3-(4-allyloxyphenyl)-2-aminopropanoate hydrochloride (138535-28-1) + Fmoc-Lys(tert-butoxycarbonyl) (71989-26-9) → methyl (2S,5S)-2-(4-allyloxybenzyl)-3-aza-9-(tert-butoxycarbonylamino)-5-(9H-9-fluorenylmethyloxycarbonylamino)-4-oxononanoate (900521-37-1)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 16h;

DOI:10.1016/j.tet.2008.09.031

Reference yield: 77.0%

→ methyl (2S,5S)-2-(4-allyloxybenzyl)-3-aza-9-(tert-butoxycarbonylamino)-5-(9H-9-fluorenylmethyloxycarbonylamino)-4-oxononanoate (900521-37-1)

Guidance literature:

upstream raw materials:

methyl (2S)-3-(4-allyloxyphenyl)-2-aminopropanoate hydrochloride

Fmoc-Lys(tert-butoxycarbonyl)