4-tolyl(2,6-bis(dimethylaminomethyl)phenyl-N,C,N)platinum(II)

Base Information

• Chemical Name: 4-tolyl(2,6-bis(dimethylaminomethyl)phenyl-N,C,N)platinum(II)
• CAS No.: 95532-51-7
• Molecular Formula: C₁₉H₂₆N₂Pt
• Molecular Weight: 477.509
• Mol file: 95532-51-7.mol

Synonyms:4-tolyl(2,6-bis(dimethylaminomethyl)phenyl-N,C,N)platinum(II)

Chemical Property of 4-tolyl(2,6-bis(dimethylaminomethyl)phenyl-N,C,N)platinum(II)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-tolyl(2,6-bis(dimethylaminomethyl)phenyl-N,C,N)platinum(II)

There total 2 articles about 4-tolyl(2,6-bis(dimethylaminomethyl)phenyl-N,C,N)platinum(II) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

[2,6-bis(dimethylaminomethyl)-1-phenyl]platinium bromide + p-tolyllithium (2417-95-0) → 4-tolyl(2,6-bis(dimethylaminomethyl)phenyl-N,C,N)platinum(II) (95532-51-7)

Guidance literature:

In diethyl ether; byproducts: LiBr; (N2), soln. of the Li-compd. added to a suspn. of the complex in ether at 223 K, stirred at room temp. for 20 min; pptn. filtered off, washed with cold pentane, extd. with benzene, extract concd., pentane added, recrystd. from CH2Cl2/pentane, elem. anal.;

DOI:10.1016/0022-328X(86)80460-0

Reference yield: 62.0%

chloro(2,6-bis(dimethylaminomethyl)phenyl-N,C,N)platinum(II) (663164-11-2) + p-tolyllithium (2417-95-0) → 4-tolyl(2,6-bis(dimethylaminomethyl)phenyl-N,C,N)platinum(II) (95532-51-7)

Guidance literature:

In diethyl ether; under Ar; CH3C6H4Li (4.2 equiv.) dissolved in dry Et2O; filtered into cooled (-78°C) suspn. of Pt complex in dry Et2O; stirred at low temp. for 20 min and at ambient temp. for 2 h; solvent removed in vac.; CH2Cl2 added; filtered through Celite; vol. of filtrate reduced; pentane added; solid collected; washed with Et2O; dried in vac.;

DOI:10.1021/om040061w

Reference yield: 61.0%

4-tolyl(2,6-bis(dimethylaminomethyl)phenyl-N,C,N)platinum(II) (95532-51-7) → cis-((2,6-bis{(dimethylamino)methyl}phenyl)(4-tolyl)platinum)(VI) diiodide (125542-13-4)

Guidance literature:

With iodine; In benzene; addn. of benzene soln. of I2 to stirring soln. of Pt-compd. in benzene dropwise, stirring (20 min); concn. of vol. to 4 ml, pptn. by addn. of pentane, filtration, washing (pentane), recrystn. (CH2Cl2/pentane); elem. anal.;

upstream raw materials:

p-tolyllithium

chloro(2,6-bis(dimethylaminomethyl)phenyl-N,C,N)platinum(II)

Downstream raw materials:

cis-{Pt(4-tolyl)Br₂(C₆H₃(CH₂NMe₂)2-2,6)}

cis-((2,6-bis{(dimethylamino)methyl}phenyl)(4-tolyl)platinum)(VI) diiodide

cis-4-tolylbis(benzoato)(2,6-bis(dimethylaminomethyl)phenyl-N,C,N)platinum(IV)

benzoato(2,6-bis(dimethylaminomethyl)phenyl-N,C,N)platinum(II)