7-amino-8-(4-fluorophenylacetylamino)-2-phenyl-1,2,4-triazolo<1,5-c>pyrimidine

Base Information

Chemical Name:7-amino-8-(4-fluorophenylacetylamino)-2-phenyl-1,2,4-triazolo<1,5-c>pyrimidine
CAS No.:159976-49-5
Molecular Formula:C₁₉H₁₅FN₆O
Molecular Weight:362.366
Hs Code.:

Synonyms:7-amino-8-(4-fluorophenylacetylamino)-2-phenyl-1,2,4-triazolo<1,5-c>pyrimidine

Suppliers and Price of 7-amino-8-(4-fluorophenylacetylamino)-2-phenyl-1,2,4-triazolo<1,5-c>pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 7-amino-8-(4-fluorophenylacetylamino)-2-phenyl-1,2,4-triazolo<1,5-c>pyrimidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 7-amino-8-(4-fluorophenylacetylamino)-2-phenyl-1,2,4-triazolo<1,5-c>pyrimidine

There total 5 articles about 7-amino-8-(4-fluorophenylacetylamino)-2-phenyl-1,2,4-triazolo<1,5-c>pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 159976-47-3
7,8-diamino-2-phenyl-1,2,4-triazolo<1,5-c>pyrimidine

: 459-04-1
4-Fluorophenylacetyl chloride

: 159976-49-5
7-amino-8-(4-fluorophenylacetylamino)-2-phenyl-1,2,4-triazolo<1,5-c>pyrimidine

Guidance literature:: With pyridine; for 2h; Ambient temperature;
DOI:10.1002/jhet.5570310512

Reference yield:

: 613-94-5
benzoic acid hydrazide

: 159976-49-5
7-amino-8-(4-fluorophenylacetylamino)-2-phenyl-1,2,4-triazolo<1,5-c>pyrimidine

Guidance literature:: Multi-step reaction with 5 steps

1: 88 percent / Et₃N / dioxane / 1 h / Ambient temperature

2: 83 percent / polyphosphoric acid / 3 h / 120 - 130 °C

3: 94 percent / trifluoroacetic acid / 5 h / Heating

4: 28 percent / H₂ / 10percent Pd/C / 12 h / 2280 Torr / Ambient temperature

5: 68 percent / pyridine / 2 h / Ambient temperature

With pyridine; PPA; hydrogen; triethylamine; trifluoroacetic acid; palladium on activated charcoal; In 1,4-dioxane;
DOI:10.1002/jhet.5570310512

Reference yield:

: 159976-43-9
2-nitro-2-(3-phenyl-1,2,4-triazol-5-yl)-1,1-ethenediamine

: 159976-49-5
7-amino-8-(4-fluorophenylacetylamino)-2-phenyl-1,2,4-triazolo<1,5-c>pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / trifluoroacetic acid / 5 h / Heating

2: 28 percent / H₂ / 10percent Pd/C / 12 h / 2280 Torr / Ambient temperature

3: 68 percent / pyridine / 2 h / Ambient temperature

With pyridine; hydrogen; trifluoroacetic acid; palladium on activated charcoal;
DOI:10.1002/jhet.5570310512