(1,5-bis(trimethylsilyl)penta-1,4-diyn-3-ylidene)(2,4,6-tri-tertbutylphenyl) phosphinegold chloride

Base Information

• Chemical Name: (1,5-bis(trimethylsilyl)penta-1,4-diyn-3-ylidene)(2,4,6-tri-tertbutylphenyl) phosphinegold chloride
• CAS No.: 1198424-77-9
• Molecular Formula: C₂₉H₄₇PSi₂
• Molecular Weight: 482.837
• Mol file: 1198424-77-9.mol

Synonyms:(1,5-bis(trimethylsilyl)penta-1,4-diyn-3-ylidene)(2,4,6-tri-tertbutylphenyl) phosphinegold chloride

Chemical Property of (1,5-bis(trimethylsilyl)penta-1,4-diyn-3-ylidene)(2,4,6-tri-tertbutylphenyl) phosphinegold chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1,5-bis(trimethylsilyl)penta-1,4-diyn-3-ylidene)(2,4,6-tri-tertbutylphenyl) phosphinegold chloride

There total 2 articles about (1,5-bis(trimethylsilyl)penta-1,4-diyn-3-ylidene)(2,4,6-tri-tertbutylphenyl) phosphinegold chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

1-chloro-1,5-bis(trimethylsilyl)-1,2-pentadien-4-yne (1198424-83-7) + 2,4,6-tri-t-butylphenylphosphonous dichloride (79074-00-3) → (1,5-bis(trimethylsilyl)penta-1,4-diyn-3-ylidene)(2,4,6-tri-tertbutylphenyl) phosphinegold chloride (1198424-77-9)

Guidance literature:

1-chloro-1,5-bis(trimethylsilyl)-1,2-pentadien-4-yne; 2,4,6-tri-t-butylphenylphosphonous dichloride; With lithium diisopropyl amide; In tetrahydrofuran; at -98 - -30 ℃; for 1.25h; Inert atmosphere;

With ammonium chloride; In tetrahydrofuran; water; regioselective reaction;

DOI:10.1021/jo901942u

Reference yield: 23.0%

3-bromo-1,4-bis(trimethylsilyl)penta-1,4-diyne (54623-68-6) + 2,4,6-tri-t-butylphenylphosphonous dichloride (79074-00-3) → (1,5-bis(trimethylsilyl)penta-1,4-diyn-3-ylidene)(2,4,6-tri-tertbutylphenyl) phosphinegold chloride (1198424-77-9)

Guidance literature:

3-bromo-1,4-bis(trimethylsilyl)penta-1,4-diyne; In tetrahydrofuran; at 20 ℃; for 1.25h;

2,4,6-tri-t-butylphenylphosphonous dichloride; In tetrahydrofuran; at 0 ℃; for 3h;

With 1,4-diaza-bicyclo[2.2.2]octane; In tetrahydrofuran; for 14h;

DOI:10.1080/10426507.2012.743146

Reference yield: 96.0%

(tetrahydrothiophene)gold(I) chloride (39929-21-0) + (1,5-bis(trimethylsilyl)penta-1,4-diyn-3-ylidene)(2,4,6-tri-tertbutylphenyl) phosphinegold chloride (1198424-77-9) → (1,5-bis(trimethylsilyl)penta-1,4-diyn-3-ylidene)(2,4,6-tri-tertbutylphenyl) phosphinegold chloride

Guidance literature:

In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1002/anie.201504834

upstream raw materials:

1-chloro-1,5-bis(trimethylsilyl)-1,2-pentadien-4-yne

2,4,6-tri-t-butylphenylphosphonous dichloride

3-bromo-1,4-bis(trimethylsilyl)penta-1,4-diyne

Downstream raw materials:

methoxy(penta-1,2-dien-4-yn-3-yl)(2,4,6-tri-tert-butylphenyl)phosphine

(Z)-(1-(4-nitrophenyl)-5-(trimethylsilyl)penta-1,4-diyn-3-ylidene)(2,4,6-tri-tert-butylphenyl)phosphine

(1,5-diphenylpenta-1,4-diyn-3-ylidene)(2,4,6-tri-tert-butylphenyl)phosphine

(Z)-(1-(4-nitrophenyl)-5-phenylpenta-1,4-diyn-3-ylidene)(2,4,6-tri-tert-butylphenyl)phosphine