2,4,6-tri-t-butylphenylphosphonous dichloride

Base Information

• Chemical Name: 2,4,6-tri-t-butylphenylphosphonous dichloride
• CAS No.: 79074-00-3
• Molecular Formula: C₁₈H₂₉Cl₂P
• Molecular Weight: 347.308
• Mol file: 79074-00-3.mol

Synonyms:2,4,6-tri-t-butylphenylphosphonous dichloride

Chemical Property of 2,4,6-tri-t-butylphenylphosphonous dichloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,4,6-tri-t-butylphenylphosphonous dichloride

There total 8 articles about 2,4,6-tri-t-butylphenylphosphonous dichloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

1-bromo-2,4,6-tri-tert-butylbenzene (3975-77-7) → 2,4,6-tri-t-butylphenylphosphonous dichloride (79074-00-3)

Guidance literature:

1-bromo-2,4,6-tri-tert-butylbenzene; With magnesium; In tetrahydrofuran; for 1h; Inert atmosphere; Schlenk technique; Reflux;

With 1,4-dioxane; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere; Schlenk technique;

With phosphorus trichloride; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.201806334

Reference yield:

Bis(2,4,6-tri-tert-butylphenyl)diphosphen (83466-54-0,93602-74-5,79073-99-7) → 2,4,6-tri-t-butylphenylphosphonous dichloride (79074-00-3)

Guidance literature:

With chlorine; In tetrachloromethane; Ambient temperature;

DOI:10.1021/ja00405a054

Reference yield:

chloro-trimethyl-silane (75-77-4) + (2,4,6-tri-tert-butylphenyl)phosphine (83115-12-2) → 2,4,6-tri-t-butylphenylphosphonous dichloride (79074-00-3)

Guidance literature:

(2,4,6-tri-tert-butylphenyl)phosphine; With n-butyllithium; In tetrahydrofuran; at -80 ℃; for 0.5h; Inert atmosphere;

chloro-trimethyl-silane; In tetrahydrofuran; Inert atmosphere;

DOI:10.1039/c5dt02757h

upstream raw materials:

1-bromo-2,4,6-tri-tert-butylbenzene

mesityl[bis(trimethylsilyl)]phosphine

Bis(2,4,6-tri-tert-butylphenyl)diphosphen

2,6,2'',6''-tetramethyl-1,1':3',1''-terphenyl

Downstream raw materials:

2,2-dichloro-1-(2,4,6-tri-tert-butylphenyl)-1-phosphaethene

(E/Z)-(Bromomethylene)(2,4,6-tri-tert-butylphenyl)phosphane

Inden-(1E)-ylidene-(2,4,6-tri-tert-butyl-phenyl)-phosphane

3,3,4,4-Tetrafluoro-2-(2,4,6-tri-tert-butyl-phenyl)-[1,2]thiaphosphetane 2-sulfide

Refernces

• 1、 Bresien, Jonas,Schulz, Axel,Villinger, Alexander. "Low temperature isolation of a dinuclear silver complex of the cyclotetraphosphane [ClP(μ-PMes?)]2". . p. 498 - 501. Retrieved 2015.
• 2、 Gupta, Priyanka,Siewert, Jan-Erik,Wellnitz, Tim,Fischer, Malte,Baumann, Wolgang,Beweries, Torsten,Hering-Junghans, Christian. "Reactivity of phospha-Wittig reagents towards NHCs and NHOs". supporting information. p. 1838 - 1844. Retrieved 2021/02/16.
• 3、 Morales Salazar, Daniel,Mijangos, Edgar,Pullen, Sonja,Gao, Ming,Orthaber, Andreas. "Functional small-molecules & polymers containing P=C and As=C bonds as hybrid π-conjugated materials". supporting information. p. 1120 - 1123. Retrieved 2017/02/05.