10-(4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)butyl)-2-(trifluoromethyl)-10H-phenothiazine

Base Information

• Chemical Name: 10-(4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)butyl)-2-(trifluoromethyl)-10H-phenothiazine
• CAS No.: 1387626-83-6
• Molecular Formula: C₂₅H₂₂F₃N₅OS
• Molecular Weight: 497.544

Synonyms:10-(4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)butyl)-2-(trifluoromethyl)-10H-phenothiazine

Chemical Property of 10-(4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)butyl)-2-(trifluoromethyl)-10H-phenothiazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 10-(4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)butyl)-2-(trifluoromethyl)-10H-phenothiazine

There total 3 articles about 10-(4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)butyl)-2-(trifluoromethyl)-10H-phenothiazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

10-((1E,3Z)-4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)buta-1,3-dien-1-yl)-2-(trifluoromethyl)-10H-phenothiazine (742105-64-2) → 10-(4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)butyl)-2-(trifluoromethyl)-10H-phenothiazine (1387626-83-6)

Guidance literature:

With palladium on activated charcoal; hydrogen; triethylamine; In methanol; dichloromethane; at 20 ℃; for 24h; under 760.051 Torr;

DOI:10.1016/j.bmc.2012.05.065

Reference yield:

2-(trifluoromethyl)-10H-phenothiazine (92-30-8) → 10-(4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)butyl)-2-(trifluoromethyl)-10H-phenothiazine (1387626-83-6)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydride / tetrahydrofuran; mineral oil / 48.33 h

2: palladium on activated charcoal; hydrogen; triethylamine / methanol; dichloromethane / 24 h / 20 °C / 760.05 Torr

With palladium on activated charcoal; hydrogen; sodium hydride; triethylamine; In tetrahydrofuran; methanol; dichloromethane; mineral oil;

DOI:10.1016/j.bmc.2012.05.065

Reference yield:

3-(4-methoxyphenyl)-tetrazolo[1,5-a]pyridin-4-ium tetrafluoroborate → 10-(4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)butyl)-2-(trifluoromethyl)-10H-phenothiazine (1387626-83-6)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydride / tetrahydrofuran; mineral oil / 48.33 h

2: palladium on activated charcoal; hydrogen; triethylamine / methanol; dichloromethane / 24 h / 20 °C / 760.05 Torr

With palladium on activated charcoal; hydrogen; sodium hydride; triethylamine; In tetrahydrofuran; methanol; dichloromethane; mineral oil;

DOI:10.1016/j.bmc.2012.05.065

upstream raw materials:

10-((1E,3Z)-4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)buta-1,3-dien-1-yl)-2-(trifluoromethyl)-10H-phenothiazine

2-(trifluoromethyl)-10H-phenothiazine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1387626-83-6 10-(4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)butyl)-2-(trifluoromethyl)-10H-phenothiazine

Send

Send

Metric Ton KG G Pound L ML

Send

Send