10-((1E,3Z)-4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)buta-1,3-dien-1-yl)-2-(trifluoromethyl)-10H-phenothiazine

Base Information

Chemical Name:10-((1E,3Z)-4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)buta-1,3-dien-1-yl)-2-(trifluoromethyl)-10H-phenothiazine
CAS No.:742105-64-2
Molecular Formula:C₂₅H₁₈F₃N₅OS
Molecular Weight:493.512
Hs Code.:

Synonyms:10-((1E,3Z)-4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)buta-1,3-dien-1-yl)-2-(trifluoromethyl)-10H-phenothiazine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 10-((1E,3Z)-4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)buta-1,3-dien-1-yl)-2-(trifluoromethyl)-10H-phenothiazine

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Technology Process of 10-((1E,3Z)-4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)buta-1,3-dien-1-yl)-2-(trifluoromethyl)-10H-phenothiazine

There total 1 articles about 10-((1E,3Z)-4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)buta-1,3-dien-1-yl)-2-(trifluoromethyl)-10H-phenothiazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 92-30-8
2-(trifluoromethyl)-10H-phenothiazine

: 3-(4-methoxyphenyl)-tetrazolo[1,5-a]pyridin-4-ium tetrafluoroborate

: 742105-64-2
10-((1E,3Z)-4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)buta-1,3-dien-1-yl)-2-(trifluoromethyl)-10H-phenothiazine

Guidance literature:: With sodium hydride; In tetrahydrofuran; mineral oil; for 48.3333h;
DOI:10.1016/j.bmc.2012.05.065

Reference yield: 99.0%

: 742105-64-2
10-((1E,3Z)-4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)buta-1,3-dien-1-yl)-2-(trifluoromethyl)-10H-phenothiazine

: 1387626-83-6
10-(4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)butyl)-2-(trifluoromethyl)-10H-phenothiazine

Guidance literature:: With palladium on activated charcoal; hydrogen; triethylamine; In methanol; dichloromethane; at 20 ℃; for 24h; under 760.051 Torr;
DOI:10.1016/j.bmc.2012.05.065

Reference yield:

: 742105-64-2
10-((1E,3Z)-4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)buta-1,3-dien-1-yl)-2-(trifluoromethyl)-10H-phenothiazine

: C₂₅H₂₃BF₃N₅OS

Guidance literature:: With dimethylsulfide borane complex; In tetrahydrofuran; at 0 - 20 ℃; for 24h; Inert atmosphere;
DOI:10.1016/j.bmc.2012.05.065