(R)-N-(2,4-dimethoxybenzyl)-N-(2-hydroxypropyl)-3,3-dimethoxypropanamide

Base Information

Chemical Name:(R)-N-(2,4-dimethoxybenzyl)-N-(2-hydroxypropyl)-3,3-dimethoxypropanamide
CAS No.:1623766-30-2
Molecular Formula:C₁₇H₂₇NO₆
Molecular Weight:341.404
Hs Code.:

Synonyms:(R)-N-(2,4-dimethoxybenzyl)-N-(2-hydroxypropyl)-3,3-dimethoxypropanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-N-(2,4-dimethoxybenzyl)-N-(2-hydroxypropyl)-3,3-dimethoxypropanamide

Chemical Property:

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Technology Process of (R)-N-(2,4-dimethoxybenzyl)-N-(2-hydroxypropyl)-3,3-dimethoxypropanamide

There total 2 articles about (R)-N-(2,4-dimethoxybenzyl)-N-(2-hydroxypropyl)-3,3-dimethoxypropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6191-98-6
3,3-dimethoxypropionic acid

: 1604440-58-5
(R)-1-((2,4-dimethoxybenzyl)amino)propan-2-ol

: 1623766-30-2
(R)-N-(2,4-dimethoxybenzyl)-N-(2-hydroxypropyl)-3,3-dimethoxypropanamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 14h;

Reference yield:

: 613-45-6
2,4-Dimethoxybenzaldehyde

: 1623766-30-2
(R)-N-(2,4-dimethoxybenzyl)-N-(2-hydroxypropyl)-3,3-dimethoxypropanamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic acid / tetrahydrofuran / 1 h / 20 °C

1.2: 18 h / 20 °C

2.1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 14 h / 20 °C

With benzotriazol-1-ol; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; N,N-dimethyl-formamide;