3-<4-(2-phenylethyl)>benzoylacrylic cid

Base Information

• Chemical Name: 3-<4-(2-phenylethyl)>benzoylacrylic cid
• CAS No.: 122399-71-7
• Molecular Formula: C₁₈H₁₆O₃
• Molecular Weight: 280.323
• Mol file: 122399-71-7.mol

Synonyms:3-<4-(2-phenylethyl)>benzoylacrylic cid

Chemical Property of 3-<4-(2-phenylethyl)>benzoylacrylic cid

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 3-<4-(2-phenylethyl)>benzoylacrylic cid

There total 1 articles about 3-<4-(2-phenylethyl)>benzoylacrylic cid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

maleic anhydride (108-31-6) + 1,1'-(1,2-ethanediyl)bisbenzene (103-29-7) → 3-<4-(2-phenylethyl)>benzoylacrylic cid (122399-71-7)

Guidance literature:

With aluminium trichloride; In dichloromethane; for 4.5h; Ambient temperature;

DOI:10.1248/cpb.37.1260

Reference yield: 94.3%

3-<4-(2-phenylethyl)>benzoylacrylic cid (122399-71-7) + tiolacetic acid (507-09-5) → 2-Acetylsulfanyl-4-oxo-4-(4-phenethyl-phenyl)-butyric acid (122399-31-9)

Guidance literature:

In dichloromethane; for 5h; Ambient temperature;

DOI:10.1248/cpb.37.1260

Reference yield: 83.0%

3-<4-(2-phenylethyl)>benzoylacrylic cid (122399-71-7) → (±)-(E)-4-hydroxy-4-(4-phenethylphenyl)but-2-enoic acid

Guidance literature:

With sodium tetrahydroborate; cerium(III) chloride heptahydrate; In methanol; water; at 0 - 20 ℃; for 3h;

DOI:10.1021/acs.jmedchem.7b01351

upstream raw materials:

maleic anhydride

1,1'-(1,2-ethanediyl)bisbenzene

Downstream raw materials:

2-Acetylsulfanyl-4-oxo-4-(4-phenethyl-phenyl)-butyric acid