Dimethyl 2-phenyl-1,3-propenedicarboxylate

Base Information

• Chemical Name: Dimethyl 2-phenyl-1,3-propenedicarboxylate
• CAS No.: 98606-70-3
• Molecular Formula: C₁₃H₁₄O₄
• Molecular Weight: 234.252
• Mol file: 98606-70-3.mol

Synonyms:Dimethyl 2-phenyl-1,3-propenedicarboxylate

Chemical Property of Dimethyl 2-phenyl-1,3-propenedicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Dimethyl 2-phenyl-1,3-propenedicarboxylate

There total 3 articles about Dimethyl 2-phenyl-1,3-propenedicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

methanol (67-56-1) + 4-phenyl-2H-pyran-2,6(3H)-dione (25631-82-7) → Dimethyl 2-phenyl-1,3-propenedicarboxylate (98606-70-3)

Guidance literature:

With sodium hydroxide; In water; at 20 ℃;

DOI:10.1021/acs.joc.0c01717

Reference yield:

3-Hydroxy-5,5-bis-methylsulfanyl-3-phenyl-pent-4-enoic acid ethyl ester → Dimethyl 2-phenyl-1,3-propenedicarboxylate (98606-70-3)

Guidance literature:

With boron trifluoride diethyl etherate; In methanol; for 20h; Yield given; Heating;

DOI:10.1055/s-1985-31142

Reference yield:

3,3-bis(methylthio)-1-phenylprop-2-en-1-one (13636-88-9) → Dimethyl 2-phenyl-1,3-propenedicarboxylate (98606-70-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) activated zinc, iodine / 1.) ether, 0.5 h, reflux, 2.) ether, benzene, 3 h, reflux

2: BF₃*Et₂O / methanol / 20 h / Heating

With boron trifluoride diethyl etherate; iodine; zinc; In methanol;

DOI:10.1055/s-1985-31142

upstream raw materials:

3,3-bis(methylthio)-1-phenylprop-2-en-1-one

methanol

4-phenyl-2H-pyran-2,6(3H)-dione

Refernces

• 1、 Apparao, S.,Datta, A.,Ila, H.,Junjappa, H.. "Reformatsky Reaction on α-Oxoketene S,S-Acetals: Synthesis of Novel Polarized Vinylketene S,S-Acetals and Dimethyl 2-Aryl(methyl)-propene-1,3-dicarboxylates". . p. 169 - 171. Retrieved 2007/10/02.