triethyl (E,2S,3R)-(3-isopropyl-5-phenylpent-4-en-2-yloxy)silane

Base Information

• Chemical Name: triethyl (E,2S,3R)-(3-isopropyl-5-phenylpent-4-en-2-yloxy)silane
• CAS No.: 1058213-78-7
• Molecular Formula: C₂₀H₃₄OSi
• Molecular Weight: 318.575
• Mol file: 1058213-78-7.mol

Synonyms:triethyl (E,2S,3R)-(3-isopropyl-5-phenylpent-4-en-2-yloxy)silane

Chemical Property of triethyl (E,2S,3R)-(3-isopropyl-5-phenylpent-4-en-2-yloxy)silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of triethyl (E,2S,3R)-(3-isopropyl-5-phenylpent-4-en-2-yloxy)silane

There total 3 articles about triethyl (E,2S,3R)-(3-isopropyl-5-phenylpent-4-en-2-yloxy)silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

triethyl (-)-(E,2S,3R)-(3-isopropyl-5-[(S)-N-methyl-S-phenylsulfonimidoyl]pent-4-en-2-yloxy)silane (1058213-64-1) + phenyllithium (591-51-5) → biphenyl (92-52-4,1594-86-1) + triethyl (Z,2S,3R)-(3-isopropyl-5-phenylpent-4-en-2-yloxy)silane (1058213-80-1) + triethyl (E,2S,3R)-(3-isopropyl-5-phenylpent-4-en-2-yloxy)silane (1058213-78-7) + (7Z,9Z,5S,6R,12S)-3,3,14,14-tetraethyl-6,11-diisopropyl-5,12-dimethyl-8-phenyl-4,13-dioxa-3,14-disilahexadeca-7,9-diene + (+)-(S)-N-methyl benzenesulfinamide (33957-73-2)

Guidance literature:

triethyl (-)-(E,2S,3R)-(3-isopropyl-5-[(S)-N-methyl-S-phenylsulfonimidoyl]pent-4-en-2-yloxy)silane; phenyllithium; With copper(l) iodide; In diethyl ether; cyclohexane; at -15 - 0 ℃; for 3.5h; Inert atmosphere;

With ammonia; water; ammonium chloride; In diethyl ether; cyclohexane; at 0 ℃; Inert atmosphere;

DOI:10.1002/chem.200800455

Reference yield: 85.0%

C21H37NO2SSi (1058213-69-6) + phenyllithium (591-51-5) → triethyl (E,2S,3R)-(3-isopropyl-5-phenylpent-4-en-2-yloxy)silane (1058213-78-7) + (7E,9E,5S,6R,12S)-3,3,14,14-tetraethyl-6,11-diisopropyl-5,12-dimethyl-8-phenyl-4,13-dioxa-3,14-disilahexadeca-7,9-diene + (+)-(S)-N-methyl benzenesulfinamide (33957-73-2)

Guidance literature:

C₂₁H₃₇NO₂SSi; phenyllithium; With copper(l) iodide; In diethyl ether; cyclohexane; at -40 - 20 ℃; for 18h; Inert atmosphere;

With ammonia; water; ammonium chloride; In diethyl ether; cyclohexane; at 20 ℃; optical yield given as %de; Inert atmosphere;

DOI:10.1002/chem.200800455

Reference yield: 74.0%

C21H37NO2SSi (1058213-69-6) + phenyllithium (591-51-5) → triethyl (Z,2S,3R)-(3-isopropyl-5-phenylpent-4-en-2-yloxy)silane (1058213-80-1) + triethyl (E,2S,3R)-(3-isopropyl-5-phenylpent-4-en-2-yloxy)silane (1058213-78-7) + (-)-(Z,2S,3R)-3-(isopropyl)-5-phenyl-5-(triethylsilyl)pent-4-en-2-ol (1058213-77-6) + (7E,9E,5S,6R,12S)-3,3,14,14-tetraethyl-6,11-diisopropyl-5,12-dimethyl-8-phenyl-4,13-dioxa-3,14-disilahexadeca-7,9-diene

Guidance literature:

C₂₁H₃₇NO₂SSi; phenyllithium; With copper(l) iodide; In diethyl ether; at -15 - 20 ℃; for 3h; Inert atmosphere;

With ammonia; water; ammonium chloride; In diethyl ether; optical yield given as %de; Inert atmosphere;

DOI:10.1002/chem.200800455

upstream raw materials:

C₂₁H₃₇NO₂SSi

phenyllithium

triethyl (-)-(E,2S,3R)-(3-isopropyl-5-[(S)-N-methyl-S-phenylsulfonimidoyl]pent-4-en-2-yloxy)silane