4-[1-(1-tert-butyl-3,3,5,5-tetraethylpiperazin-2-on-4-yloxy)-ethyl]-benzoic acid

Base Information

Chemical Name:4-[1-(1-tert-butyl-3,3,5,5-tetraethylpiperazin-2-on-4-yloxy)-ethyl]-benzoic acid
CAS No.:1295579-03-1
Molecular Formula:C₂₅H₄₀N₂O₄
Molecular Weight:432.604
Hs Code.:

Synonyms:4-[1-(1-tert-butyl-3,3,5,5-tetraethylpiperazin-2-on-4-yloxy)-ethyl]-benzoic acid

Suppliers and Price of 4-[1-(1-tert-butyl-3,3,5,5-tetraethylpiperazin-2-on-4-yloxy)-ethyl]-benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[1-(1-tert-butyl-3,3,5,5-tetraethylpiperazin-2-on-4-yloxy)-ethyl]-benzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[1-(1-tert-butyl-3,3,5,5-tetraethylpiperazin-2-on-4-yloxy)-ethyl]-benzoic acid

There total 9 articles about 4-[1-(1-tert-butyl-3,3,5,5-tetraethylpiperazin-2-on-4-yloxy)-ethyl]-benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 124-38-9,18923-20-1
carbon dioxide

: 1295579-01-9
4-[1-(4-bromophenyl)-ethoxy]-1-tert-butyl-3,3,5,5-tetraethylpiperazin-2-one

: 1295579-03-1
4-[1-(1-tert-butyl-3,3,5,5-tetraethylpiperazin-2-on-4-yloxy)-ethyl]-benzoic acid

Guidance literature:: 4-[1-(4-bromophenyl)-ethoxy]-1-tert-butyl-3,3,5,5-tetraethylpiperazin-2-one; With tert.-butyl lithium; In tetrahydrofuran; pentane; at -78 ℃; for 0.333333h; Inert atmosphere;

carbon dioxide; In tetrahydrofuran; pentane; at -78 - 20 ℃;

With hydrogenchloride; In tetrahydrofuran; pentane; at 20 ℃;
DOI:10.1039/c0ob01047b

Reference yield:

: 264280-09-3
N-tert-butyl-2-ethylbutane-1,2-diamine

: 1295579-03-1
4-[1-(1-tert-butyl-3,3,5,5-tetraethylpiperazin-2-on-4-yloxy)-ethyl]-benzoic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: potassium hydroxide / 18 h / 10 - 20 °C

2.1: peracetic acid; acetic acid / ethyl acetate / 16 h / 0 - 20 °C / Inert atmosphere

3.1: Cu(OTf)2; copper; 4,4'-di-tert-butyl-2,2'-bipyridine / benzene / 16 h / 75 °C / Inert atmosphere

4.1: tert.-butyl lithium / tetrahydrofuran; pentane / 0.33 h / -78 °C / Inert atmosphere

4.2: -78 - 20 °C

4.3: 20 °C

With peracetic acid; Cu(OTf)2; tert.-butyl lithium; copper; acetic acid; 4,4'-di-tert-butyl-2,2'-bipyridine; potassium hydroxide; In tetrahydrofuran; ethyl acetate; pentane; benzene;
DOI:10.1039/c0ob01047b

Reference yield:

: 1141324-78-8
N-tert-butyl-(2-ethyl-2-nitrobutyl)-amine

: 1295579-03-1
4-[1-(1-tert-butyl-3,3,5,5-tetraethylpiperazin-2-on-4-yloxy)-ethyl]-benzoic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: acetic acid; zinc / water / 2 h / 20 °C / Cooling with ice

2.1: potassium hydroxide / 18 h / 10 - 20 °C

3.1: peracetic acid; acetic acid / ethyl acetate / 16 h / 0 - 20 °C / Inert atmosphere

4.1: Cu(OTf)2; copper; 4,4'-di-tert-butyl-2,2'-bipyridine / benzene / 16 h / 75 °C / Inert atmosphere

5.1: tert.-butyl lithium / tetrahydrofuran; pentane / 0.33 h / -78 °C / Inert atmosphere

5.2: -78 - 20 °C

5.3: 20 °C

With peracetic acid; Cu(OTf)2; tert.-butyl lithium; copper; acetic acid; 4,4'-di-tert-butyl-2,2'-bipyridine; potassium hydroxide; zinc; In tetrahydrofuran; water; ethyl acetate; pentane; benzene;
DOI:10.1039/c0ob01047b