(2S,3R,4R,5S)-1-butyl-3,4,5-tris(phenylmethoxy)-2-[(phenylmethoxy)methyl]piperidine

Base Information

Chemical Name:(2S,3R,4R,5S)-1-butyl-3,4,5-tris(phenylmethoxy)-2-[(phenylmethoxy)methyl]piperidine
CAS No.:441061-29-6
Molecular Formula:C₃₈H₄₅NO₄
Molecular Weight:579.78
Hs Code.:

Synonyms:(2S,3R,4R,5S)-1-butyl-3,4,5-tris(phenylmethoxy)-2-[(phenylmethoxy)methyl]piperidine

Suppliers and Price of (2S,3R,4R,5S)-1-butyl-3,4,5-tris(phenylmethoxy)-2-[(phenylmethoxy)methyl]piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,3,4,6-Tetra-O-benzyl-1-L-ido-miglustatmiglustat
10mg
$ 130.00

Total 3 raw suppliers

Chemical Property of (2S,3R,4R,5S)-1-butyl-3,4,5-tris(phenylmethoxy)-2-[(phenylmethoxy)methyl]piperidine

Chemical Property:

Purity/Quality:

95%+ or 98%+ ^*data from raw suppliers

2,3,4,6-Tetra-O-benzyl-1-L-ido-miglustatmiglustat ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 2,3,4,6-Tetra-O-benzyl-1-L-ido-miglustat is a useful reagent in preparation of pharmaceutically active aza-sugar piperidine derivatives as inhibitors of galactosidase and glucosylceramide synthase.

Technology Process of (2S,3R,4R,5S)-1-butyl-3,4,5-tris(phenylmethoxy)-2-[(phenylmethoxy)methyl]piperidine

There total 8 articles about (2S,3R,4R,5S)-1-butyl-3,4,5-tris(phenylmethoxy)-2-[(phenylmethoxy)methyl]piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 2,3,4,6-tetra-O-benzyl-1,5-di-O-mesyl-D-glucitol

: 109-73-9,85404-21-3
N-butylamine

: 441061-29-6
(2S,3R,4R,5S)-1-butyl-3,4,5-tris(phenylmethoxy)-2-[(phenylmethoxy)methyl]piperidine

Guidance literature:: at 50 ℃; for 96h;

Reference yield: 42.3%

: (2R,3R,4R,5S)-1,3,4,5-tetrakis(benzyloxy)-6-(butylamino)hexan-2-ol

: 441061-29-6
(2S,3R,4R,5S)-1-butyl-3,4,5-tris(phenylmethoxy)-2-[(phenylmethoxy)methyl]piperidine

Guidance literature:: With C₅H₁₄I₂IrN₃; In neat (no solvent); at 180 ℃; for 24h; Reagent/catalyst; stereoselective reaction; Inert atmosphere; Schlenk technique;
DOI:10.1039/c6ob01864e

Reference yield:

: 109-73-9,85404-21-3
N-butylamine

: 214041-43-7
(2R,3R,4S)-2,3,4,6-tetrakis(benzyloxy)-5-oxohexanal

: 441061-29-6
(2S,3R,4R,5S)-1-butyl-3,4,5-tris(phenylmethoxy)-2-[(phenylmethoxy)methyl]piperidine

: 227932-82-3
N-butyl 2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1,5-imino-D-glucitol

Guidance literature:: With sodium cyanoborohydride; acetic acid; sodium sulfate; In methanol; dichloromethane; at 20 ℃; for 15h; pH=6; Inert atmosphere;