5-benzoyloxy-2(E),4(E)-pentadienoyl chloride

Base Information

• Chemical Name: 5-benzoyloxy-2(E),4(E)-pentadienoyl chloride
• CAS No.: 84525-44-0
• Molecular Formula: C₁₂H₉ClO₃
• Molecular Weight: 236.655
• Mol file: 84525-44-0.mol

Synonyms:5-benzoyloxy-2(E),4(E)-pentadienoyl chloride

Chemical Property of 5-benzoyloxy-2(E),4(E)-pentadienoyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-benzoyloxy-2(E),4(E)-pentadienoyl chloride

There total 2 articles about 5-benzoyloxy-2(E),4(E)-pentadienoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-benzoyloxy-2(E),4(E)-pentadienoic acid (84541-23-1) → 5-benzoyloxy-2(E),4(E)-pentadienoyl chloride (84525-44-0)

Guidance literature:

With thionyl chloride; hydroquinone; at 50 ℃; for 2h; Yield given;

DOI:10.1055/s-1982-30020

Reference yield:

4-benzoyloxy-trans-2-trans-4-pentadienal (24338-67-8) → 5-benzoyloxy-2(E),4(E)-pentadienoyl chloride (84525-44-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / resorcinol, sodium chlorite / ethanol / 24 h / Ambient temperature; buffer (aq. solution citric acid and trisodium salt citric acid) - pH=3,6

2: thionyl chloride, hydroquinone / 2 h / 50 °C

With sodium chlorite; thionyl chloride; hydroquinone; recorcinol; In ethanol;

DOI:10.1055/s-1982-30020

Reference yield: 78.0%

5-benzoyloxy-2(E),4(E)-pentadienoyl chloride (84525-44-0) → 5-benzoyloxy-2(E),4(E)-pentadienoyl azide (84525-45-1)

Guidance literature:

With trimethylsilylazide; In dichloromethane; at 0 ℃; for 30h;

DOI:10.1055/s-1982-30020

upstream raw materials:

5-benzoyloxy-2(E),4(E)-pentadienoic acid

4-benzoyloxy-trans-2-trans-4-pentadienal

Downstream raw materials:

5-benzoyloxy-2(E),4(E)-pentadienoyl azide

Benzoic acid (1R,4R,5R)-4-ethoxycarbonylamino-5-methoxycarbonyl-cyclohex-2-enyl ester

methyl 1-benzoyloxy-4-ethoxycarbonylamino-2,5-cyclohexadien-3-carboxylate

Benzoic acid (3aS,4S,7R,7aR)-7-ethoxycarbonylamino-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-isobenzofuran-4-yl ester