Technology Process of 1-O-acetyl-2-deoxy-2-fluoro-3,5-di-O-benzoyl-α,β-D-xylofuranose
There total 11 articles about 1-O-acetyl-2-deoxy-2-fluoro-3,5-di-O-benzoyl-α,β-D-xylofuranose which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sulfuric acid;
at 5 - 30 ℃;
for 3h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 10 steps
1.1: hydrogenchloride / 21 h / 55 °C
1.2: 0.5 h / 25 °C
2.1: sulfuric acid; copper(II) sulfate / 35 °C / Inert atmosphere
3.1: pyridine / 3 h / 25 °C / Inert atmosphere
4.1: acetic acid / water / 3 h / 55 °C
5.1: sodium methylate / methanol / 16 h / 5 - 30 °C / pH > 11 / Inert atmosphere
6.1: potassium fluoride / 16 h / 5 - 40 °C / Inert atmosphere
7.1: potassium fluoride; potassium hydrogenfluoride / dichloromethane; ethylene glycol / 2 h / 35 - 165 °C / Inert atmosphere
8.1: hydrogen; palladium 10% on activated carbon / ethanol / 16 h / 25 °C
9.1: pyridine / 2 h / 5 °C / Inert atmosphere
10.1: sulfuric acid / 3 h / 5 - 30 °C / Inert atmosphere
With
pyridine; hydrogenchloride; potassium fluoride; potassium hydrogenfluoride; sulfuric acid; palladium 10% on activated carbon; hydrogen; sodium methylate; copper(II) sulfate; acetic acid;
In
methanol; ethanol; dichloromethane; water; ethylene glycol;