(+)-(2S,3S,4S,5S,6S)-6-((2S,3S,6S)-6-((R)-1-(tert-butyldiphenylsilyloxy)propan-2-yl)-3-methyltetrahydro-2H-pyran-2-yl)-3,5-dihydroxy-2,4-dimethylheptyl pivalate

Base Information

Chemical Name:(+)-(2S,3S,4S,5S,6S)-6-((2S,3S,6S)-6-((R)-1-(tert-butyldiphenylsilyloxy)propan-2-yl)-3-methyltetrahydro-2H-pyran-2-yl)-3,5-dihydroxy-2,4-dimethylheptyl pivalate
CAS No.:1333040-88-2
Molecular Formula:C₃₉H₆₂O₆Si
Molecular Weight:655.003
Hs Code.:

(+)-(2S,3S,4S,5S,6S)-6-((2S,3S,6S)-6-((R)-1-(tert-butyldiphenylsilyloxy)propan-2-yl)-3-methyltetrahydro-2H-pyran-2-yl)-3,5-dihydroxy-2,4-dimethylheptyl pivalate

Synonyms:(+)-(2S,3S,4S,5S,6S)-6-((2S,3S,6S)-6-((R)-1-(tert-butyldiphenylsilyloxy)propan-2-yl)-3-methyltetrahydro-2H-pyran-2-yl)-3,5-dihydroxy-2,4-dimethylheptyl pivalate

Suppliers and Price of (+)-(2S,3S,4S,5S,6S)-6-((2S,3S,6S)-6-((R)-1-(tert-butyldiphenylsilyloxy)propan-2-yl)-3-methyltetrahydro-2H-pyran-2-yl)-3,5-dihydroxy-2,4-dimethylheptyl pivalate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (+)-(2S,3S,4S,5S,6S)-6-((2S,3S,6S)-6-((R)-1-(tert-butyldiphenylsilyloxy)propan-2-yl)-3-methyltetrahydro-2H-pyran-2-yl)-3,5-dihydroxy-2,4-dimethylheptyl pivalate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+)-(2S,3S,4S,5S,6S)-6-((2S,3S,6S)-6-((R)-1-(tert-butyldiphenylsilyloxy)propan-2-yl)-3-methyltetrahydro-2H-pyran-2-yl)-3,5-dihydroxy-2,4-dimethylheptyl pivalate

There total 4 articles about (+)-(2S,3S,4S,5S,6S)-6-((2S,3S,6S)-6-((R)-1-(tert-butyldiphenylsilyloxy)propan-2-yl)-3-methyltetrahydro-2H-pyran-2-yl)-3,5-dihydroxy-2,4-dimethylheptyl pivalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1333041-75-0
(+)-(2S,3S,4S,5S,6S)-6-((2S,3S,6S)-6-((R)-1-(tert-butyldiphenylsilyloxy)propan-2-yl)-3-methyltetrahydro-2H-pyran-2-yl)-2,4-dimethylheptane-1,3,5-triol

: 3282-30-2
pivaloyl chloride

: 1333040-88-2
(+)-(2S,3S,4S,5S,6S)-6-((2S,3S,6S)-6-((R)-1-(tert-butyldiphenylsilyloxy)propan-2-yl)-3-methyltetrahydro-2H-pyran-2-yl)-3,5-dihydroxy-2,4-dimethylheptyl pivalate

Guidance literature:: With pyridine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1021/jo2013884

Reference yield:

: 1333041-71-6
(+)-(R)-2-((2S,5S,6S)-5-methyl-6-((2S,3S,4S,5S,6S)-3,5,7-tris-(benzyloxy)-4,6-dimethylheptan-2-yl)tetrahydro-2H-pyran-2-yl)propan-1-ol

: 1333040-88-2
(+)-(2S,3S,4S,5S,6S)-6-((2S,3S,6S)-6-((R)-1-(tert-butyldiphenylsilyloxy)propan-2-yl)-3-methyltetrahydro-2H-pyran-2-yl)-3,5-dihydroxy-2,4-dimethylheptyl pivalate

Guidance literature:: Multi-step reaction with 3 steps

1: 1H-imidazole / dichloromethane / 0 - 20 °C / Inert atmosphere

2: 20 wt.% Pd(OH)2 on activated carbon; hydrogen / tetrahydrofuran / 20 °C

3: pyridine / dichloromethane / 0 - 20 °C / Inert atmosphere

With pyridine; 1H-imidazole; 20 wt.% Pd(OH)2 on activated carbon; hydrogen; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo2013884

Reference yield:

: 1333041-73-8
(+)-tert-butyl((R)-2-((2S,5S,6S)-5-methyl-6-((2S,3S,4S,5S,6S)-3,5,7-tris(benzyloxy)-4,6-dimethylheptan-2-yl)tetrahydro-2H-pyran-2-yl)propoxy)diphenylsilane

: 1333040-88-2
(+)-(2S,3S,4S,5S,6S)-6-((2S,3S,6S)-6-((R)-1-(tert-butyldiphenylsilyloxy)propan-2-yl)-3-methyltetrahydro-2H-pyran-2-yl)-3,5-dihydroxy-2,4-dimethylheptyl pivalate

Guidance literature:: Multi-step reaction with 2 steps

1: 20 wt.% Pd(OH)2 on activated carbon; hydrogen / tetrahydrofuran / 20 °C

2: pyridine / dichloromethane / 0 - 20 °C / Inert atmosphere

With pyridine; 20 wt.% Pd(OH)2 on activated carbon; hydrogen; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo2013884