N-(2-(4-(3-(2-(4-bromophenoxy)ethoxy)-2-hydroxypropyl)piperazin-1-yl)phenyl)methanoesulfonamide

Base Information

Chemical Name:N-(2-(4-(3-(2-(4-bromophenoxy)ethoxy)-2-hydroxypropyl)piperazin-1-yl)phenyl)methanoesulfonamide
CAS No.:1579960-78-3
Molecular Formula:C₂₂H₃₀BrN₃O₅S
Molecular Weight:528.467
Hs Code.:

Synonyms:N-(2-(4-(3-(2-(4-bromophenoxy)ethoxy)-2-hydroxypropyl)piperazin-1-yl)phenyl)methanoesulfonamide

Suppliers and Price of N-(2-(4-(3-(2-(4-bromophenoxy)ethoxy)-2-hydroxypropyl)piperazin-1-yl)phenyl)methanoesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(2-(4-(3-(2-(4-bromophenoxy)ethoxy)-2-hydroxypropyl)piperazin-1-yl)phenyl)methanoesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(2-(4-(3-(2-(4-bromophenoxy)ethoxy)-2-hydroxypropyl)piperazin-1-yl)phenyl)methanoesulfonamide

There total 4 articles about N-(2-(4-(3-(2-(4-bromophenoxy)ethoxy)-2-hydroxypropyl)piperazin-1-yl)phenyl)methanoesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 1159689-74-3
C₁₁H₁₃BrO₃

: 199105-19-6
1-(2-methanesulfonylamidophenyl)piperazine

: 1579960-78-3
N-(2-(4-(3-(2-(4-bromophenoxy)ethoxy)-2-hydroxypropyl)piperazin-1-yl)phenyl)methanoesulfonamide

Guidance literature:: With ethanol; for 8h; Reflux;
DOI:10.1016/j.bmcl.2014.01.070

Reference yield:

: 34743-88-9
2-(4-bromophenoxy)ethanol

: 1579960-78-3
N-(2-(4-(3-(2-(4-bromophenoxy)ethoxy)-2-hydroxypropyl)piperazin-1-yl)phenyl)methanoesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

1.2: 10 h / Inert atmosphere; Reflux

2.1: ethanol / 8 h / Reflux

With ethanol; sodium hydride; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2014.01.070

Reference yield:

: 106-41-2
4-bromo-phenol

: 1579960-78-3
N-(2-(4-(3-(2-(4-bromophenoxy)ethoxy)-2-hydroxypropyl)piperazin-1-yl)phenyl)methanoesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydroxide / water / 24 h / 20 °C / Inert atmosphere

2.1: sodium hydride / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

2.2: 10 h / Inert atmosphere; Reflux

3.1: ethanol / 8 h / Reflux

With ethanol; sodium hydride; sodium hydroxide; In tetrahydrofuran; water;
DOI:10.1016/j.bmcl.2014.01.070