trans-N-benzyl-2,5-bis(ethoxycarbonylmethyl)pyrrolidine

Base Information

Chemical Name:trans-N-benzyl-2,5-bis(ethoxycarbonylmethyl)pyrrolidine
CAS No.:127654-98-2
Molecular Formula:C₁₉H₂₇NO₄
Molecular Weight:333.428
Hs Code.:

Synonyms:trans-N-benzyl-2,5-bis(ethoxycarbonylmethyl)pyrrolidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of trans-N-benzyl-2,5-bis(ethoxycarbonylmethyl)pyrrolidine

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Technology Process of trans-N-benzyl-2,5-bis(ethoxycarbonylmethyl)pyrrolidine

There total 18 articles about trans-N-benzyl-2,5-bis(ethoxycarbonylmethyl)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 100-39-0
benzyl bromide

: 127654-97-1
cis-2,5-bis(ethoxycarbonylmethyl)pyrrolidine

: 127654-98-2
cis-N-benzyl-2,5-bis(ethoxycarbonylmethyl)pyrrolidine

Guidance literature:: With potassium carbonate; In acetone; for 2h; Ambient temperature;

Reference yield:

: 2142-06-5
1-(phenylmethyl)-2,5-pyrrolidinedione

: 127654-98-2
cis-N-benzyl-2,5-bis(ethoxycarbonylmethyl)pyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

2: H₂ / 10percent Pd-C / HClO₄; methanol / Ambient temperature

With hydrogen; palladium on activated charcoal; In methanol; perchloric acid;
DOI:10.1021/ja00543a067

Reference yield:

: 2142-06-5
1-(phenylmethyl)-2,5-pyrrolidinedione

: 127654-98-2
trans-N-benzyl-2,5-bis(ethoxycarbonylmethyl)pyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

2: H₂ / 10percent Pd-C / HClO₄; methanol / Ambient temperature

With hydrogen; palladium on activated charcoal; In methanol; perchloric acid;
DOI:10.1021/ja00543a067