rel-(4R,5S)-1-benzyloxycarbonyl-5-hydroxy-3,3-dimethoxy-N,N-dimethylpiperidine-4-acetamide

Base Information

Chemical Name:rel-(4R,5S)-1-benzyloxycarbonyl-5-hydroxy-3,3-dimethoxy-N,N-dimethylpiperidine-4-acetamide
CAS No.:87201-87-4
Molecular Formula:C₁₉H₂₈N₂O₆
Molecular Weight:380.441
Hs Code.:

Synonyms:rel-(4R,5S)-1-benzyloxycarbonyl-5-hydroxy-3,3-dimethoxy-N,N-dimethylpiperidine-4-acetamide

Suppliers and Price of rel-(4R,5S)-1-benzyloxycarbonyl-5-hydroxy-3,3-dimethoxy-N,N-dimethylpiperidine-4-acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of rel-(4R,5S)-1-benzyloxycarbonyl-5-hydroxy-3,3-dimethoxy-N,N-dimethylpiperidine-4-acetamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of rel-(4R,5S)-1-benzyloxycarbonyl-5-hydroxy-3,3-dimethoxy-N,N-dimethylpiperidine-4-acetamide

There total 4 articles about rel-(4R,5S)-1-benzyloxycarbonyl-5-hydroxy-3,3-dimethoxy-N,N-dimethylpiperidine-4-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 87202-01-5
rel-(4R,5S)-1-benzyloxycarbonyl-5-hydroxy-3,3-dimethoxypiperidine-4-acetic acid γ-lactone

: 124-40-3
dimethyl amine

: 87201-87-4
rel-(4R,5S)-1-benzyloxycarbonyl-5-hydroxy-3,3-dimethoxy-N,N-dimethylpiperidine-4-acetamide

Guidance literature:: In ethanol; water; for 0.333333h; Heating;
DOI:10.1248/cpb.31.1235

Reference yield:

: 87201-95-4
benzyl 8-hydroxy-5,5-dimethoxy-3-azabicyclo<4.2.0>octane-3-carboxylate

: 87201-87-4
rel-(4R,5S)-1-benzyloxycarbonyl-5-hydroxy-3,3-dimethoxy-N,N-dimethylpiperidine-4-acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / PCC, NaOAc / CH₂Cl₂ / 5 h / Ambient temperature

2: 61 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 1.) r.t., 15 h, 2.) reflux, 7 h

3: 98 percent / H₂O; ethanol / 0.33 h / Heating

With sodium acetate; 3-chloro-benzenecarboperoxoic acid; pyridinium chlorochromate; In ethanol; dichloromethane; water;
DOI:10.1248/cpb.31.1235

Reference yield:

: 87201-90-9
benzyl 5,5-dimethoxy-8-oxo-3-azabicyclo<4.2.0>octane-3-carboxylate

: 87201-87-4
rel-(4R,5S)-1-benzyloxycarbonyl-5-hydroxy-3,3-dimethoxy-N,N-dimethylpiperidine-4-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 1.) r.t., 15 h, 2.) reflux, 7 h

2: 98 percent / H₂O; ethanol / 0.33 h / Heating

With 3-chloro-benzenecarboperoxoic acid; In ethanol; dichloromethane; water;
DOI:10.1248/cpb.31.1235