(2-Aminobenzyl)triphenylphosphonium bromide

Base Information

Chemical Name:(2-Aminobenzyl)triphenylphosphonium bromide
CAS No.:78133-84-3
Molecular Formula:C25H23 N P . Br
Molecular Weight:448.342
Hs Code.:
European Community (EC) Number:624-626-4
DSSTox Substance ID:DTXSID50449889
Mol file:78133-84-3.mol

Synonyms:(2-aminobenzyl)triphenylphosphonium bromide

Suppliers and Price of (2-Aminobenzyl)triphenylphosphonium bromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(2-Aminobenzyl)triphenylphosphonium bromide 97%
5g
$ 131.00

American Custom Chemicals Corporation
(2-AMINOBENZYL)TRIPHENYLPHOSPHONIUM BROMIDE 95.00%
5G
$ 896.34

AK Scientific
(2-Aminobenzyl)triphenylphosphonium bromide
25g
$ 1535.00

AHH
(2-Aminobenzyl)triphenylphosphonium bromide 97%
50g
$ 280.00

Total 7 raw suppliers

Chemical Property of (2-Aminobenzyl)triphenylphosphonium bromide

Chemical Property:

Melting Point:245 °C (dec.)(lit.)
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:447.07515
Heavy Atom Count:28
Complexity:386

Purity/Quality:

98%,99%, ^*data from raw suppliers

(2-Aminobenzyl)triphenylphosphonium bromide 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)[P+](CC2=CC=CC=C2N)(C3=CC=CC=C3)C4=CC=CC=C4.[Br-]
Uses Reactant for:Intramolecular Wittig reactionPreparation of 2,3-disubstituted indolesPreparation of pyrrolocarbazoles as poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors

Technology Process of (2-Aminobenzyl)triphenylphosphonium bromide

There total 3 articles about (2-Aminobenzyl)triphenylphosphonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 23308-83-0
(2-nitrobenzyl)triphenylphosphonium bromide

: 78133-84-3
(2-aminobenzyl)triphenylphosphonium bromide

Guidance literature:: With hydrogen bromide; zinc; In ethanol;

Reference yield: 88.0%

: 5344-90-1
2-Aminobenzyl alcohol

: 6399-81-1
triphenylphosphine hydrobromide

: 78133-84-3
(2-aminobenzyl)triphenylphosphonium bromide

Guidance literature:: In acetonitrile; for 6h; Heating;

Reference yield:

: 88-72-2
1-methyl-2-nitrobenzene

: 78133-84-3
(2-aminobenzyl)triphenylphosphonium bromide

Guidance literature:: Multi-step reaction with 3 steps

1: N-bromosuccinimide (NBS), peroxyde de benzoyle / CCl₄

2: 69 percent / toluene / 1.) 3h, RT, 2.) 2h, reflux

3: 94 percent / 48percent HBr, Zn / ethanol / 2 h / Heating

With N-Bromosuccinimide; Perbenzoic acid; hydrogen bromide; zinc; In tetrachloromethane; ethanol; toluene;
DOI:10.1016/S0040-4020(01)96783-3