[4-amino-2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenylamino]-thiazol-5-yl]-(3-fluoro-phenyl)-methanone acetate

Base Information

Chemical Name:[4-amino-2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenylamino]-thiazol-5-yl]-(3-fluoro-phenyl)-methanone acetate
CAS No.:627462-77-5
Molecular Formula:C₂H₄O₂*C₂₂H₂₃FN₄O₂S
Molecular Weight:486.567
Hs Code.:

Synonyms:[4-amino-2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenylamino]-thiazol-5-yl]-(3-fluoro-phenyl)-methanone acetate

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Chemical Property of [4-amino-2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenylamino]-thiazol-5-yl]-(3-fluoro-phenyl)-methanone acetate

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Technology Process of [4-amino-2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenylamino]-thiazol-5-yl]-(3-fluoro-phenyl)-methanone acetate

There total 1 articles about [4-amino-2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenylamino]-thiazol-5-yl]-(3-fluoro-phenyl)-methanone acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 420-04-2
CYANAMID

: 53631-18-8
2-bromo-1-(3-fluorophenyl)ethanone

: 50609-00-2
1-[2-(4-isothiocyanato-phenoxy)-ethyl]-pyrrolidine

: 627462-77-5
[4-amino-2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenylamino]-thiazol-5-yl]-(3-fluoro-phenyl)-methanone acetate

Guidance literature:: CYANAMID; 1-[2-(4-isothiocyanato-phenoxy)-ethyl]-pyrrolidine; With potassium tert-butylate; In acetonitrile; tert-butyl alcohol; for 1h;

2-bromo-1-(3-fluorophenyl)ethanone; In acetonitrile; tert-butyl alcohol; at 20 ℃; for 4h;