3-amino-4-methoxy-cinnamic acid

Base Information

• Chemical Name: 3-amino-4-methoxy-cinnamic acid
• CAS No.: 58435-27-1
• Molecular Formula: C₁₀H₁₁NO₃
• Molecular Weight: 193.202
• Mol file: 58435-27-1.mol

Synonyms:3-amino-4-methoxy-cinnamic acid

Chemical Property of 3-amino-4-methoxy-cinnamic acid

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-amino-4-methoxy-cinnamic acid

There total 6 articles about 3-amino-4-methoxy-cinnamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methoxy-3-nitro-cinnamic acid (58435-22-6) → 3-amino-4-methoxy-cinnamic acid (58435-27-1)

Guidance literature:

With ammonium hydroxide; iron(II) sulfate;

Reference yield:

(E)-3-(4-methoxy-3-nitrophenyl)acrylic acid (58435-22-6) → 3-amino-4-methoxy-trans-cinnamic acid (58435-27-1)

Guidance literature:

With sodium sulfide; sodium hydroxide;

Reference yield:

4-methoxy-benzaldehyde (123-11-5) → 3-amino-4-methoxy-trans-cinnamic acid (58435-27-1)

Guidance literature:

Multi-step reaction with 3 steps

1: water; concentrated sulfuric acid; nitric acid / -15 - -10 °C

2: pyridine; piperidine

3: aq. NaOH solution; sodium sulfide

With piperidine; pyridine; sodium sulfide; sodium hydroxide; sulfuric acid; water; nitric acid;

upstream raw materials:

4-methoxy-3-nitro-cinnamic acid

(E)-3-(4-methoxy-3-nitrophenyl)acrylic acid

4-methoxy-benzaldehyde

4-methoxy-3-nitrobenzaldehyde

Downstream raw materials:

isoferulic acid

3-(3-acetoxy-4-methoxyphenyl)acrylic acid