C₁₁H₆BrF₂NOS

Base Information

• Chemical Name: C₁₁H₆BrF₂NOS
• CAS No.: 1599475-28-1
• Molecular Formula: C₁₁H₆BrF₂NOS
• Molecular Weight: 318.142
• Mol file: 1599475-28-1.mol

Synonyms:C₁₁H₆BrF₂NOS

Chemical Property of C₁₁H₆BrF₂NOS

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₁H₆BrF₂NOS

There total 1 articles about C₁₁H₆BrF₂NOS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C13H8BrF2NO2S (1599475-27-0) → C11H6BrF2NOS (1599475-28-1)

Guidance literature:

With water; sodium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 0.5h;

Reference yield: 9.0%

C8H10BN3O2S (1599475-26-9) + C11H6BrF2NOS (1599475-28-1) → N-(2,6-difluorophenyl)-5-(1-ethyl-3-(thiazol-2-yl)-1H-pyrazol-5-yl)thiophene-2-carboxamide (1599475-03-2)

Guidance literature:

With potassium phosphate; bis(di-tert-?butyl(4-?dimethylaminophenyl)?phosphine)?dichloropalladium(II); In 1,4-dioxane; acetonitrile; at 90 ℃; for 2h; Inert atmosphere;

Reference yield: 7.0%

C8H8BN3O2S (1599475-35-0) + C11H6BrF2NOS (1599475-28-1) → 2,6-difluoro-N-(5-(3-(thiazol-2-yl)-1-vinyl-1H-pyrazol-5-yl)thiophen-2-yl)benzamide (1599475-11-2)

Guidance literature:

With potassium phosphate; bis(di-tert-?butyl(4-?dimethylaminophenyl)?phosphine)?dichloropalladium(II); In 1,4-dioxane; acetonitrile; at 90 ℃; for 2h; Inert atmosphere;

upstream raw materials:

C₁₃H₈BrF₂NO₂S

Downstream raw materials:

N-(2,6-difluorophenyl)-5-(1-ethyl-3-(thiazol-2-yl)-1H-pyrazol-5-yl)thiophene-2-carboxamide

2,6-difluoro-N-(5-(3-(thiazol-2-yl)-1-vinyl-1H-pyrazol-5-yl)thiophen-2-yl)benzamide