2,2'-Methylenebis[3-bromo-6-(1,1-dimethylethyl)phenol]

Base Information

Chemical Name:2,2'-Methylenebis[3-bromo-6-(1,1-dimethylethyl)phenol]
CAS No.:159390-39-3
Molecular Formula:C₂₁H₂₆Br₂O₂
Molecular Weight:470.244
Hs Code.:
DSSTox Substance ID:DTXSID601211745

Synonyms:DTXSID601211745;2,2'-Methylenebis[3-bromo-6-(1,1-dimethylethyl)phenol];159390-39-3

Suppliers and Price of 2,2'-Methylenebis[3-bromo-6-(1,1-dimethylethyl)phenol]

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,2'-Methylenebis[3-bromo-6-(1,1-dimethylethyl)phenol]

Chemical Property:

XLogP3:7.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:470.02791
Heavy Atom Count:25
Complexity:400

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)C1=C(C(=C(C=C1)Br)CC2=C(C=CC(=C2O)C(C)(C)C)Br)O

Technology Process of 2,2'-Methylenebis[3-bromo-6-(1,1-dimethylethyl)phenol]

There total 2 articles about 2,2'-Methylenebis[3-bromo-6-(1,1-dimethylethyl)phenol] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 30715-50-5
5-bromo-2-tert-butyl-phenol

: 159390-39-3
2,2'-Methylenebis<3-bromo-6-(1,1-dimethylethyl)phenol>

Guidance literature:: With ethylmagnesium bromide; 1.) ether, 2.) benzene, reflux, 12 h;
DOI:10.1021/jo00104a040

Reference yield:

: 30788-02-4
5-Bromo-2-(1,1-dimethylethyl)-1-methoxybenzene

: 159390-39-3
2,2'-Methylenebis<3-bromo-6-(1,1-dimethylethyl)phenol>

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / BBr₃ / CH₂Cl₂ / 1.) -78 deg C, 30 min, 2.) 25 deg C, 12 h

2: 56 percent / EtMgBr / 1.) ether, 2.) benzene, reflux, 12 h

With ethylmagnesium bromide; boron tribromide; In dichloromethane;
DOI:10.1021/jo00104a040

Reference yield: 92.0%

: 159390-39-3
2,2'-Methylenebis<3-bromo-6-(1,1-dimethylethyl)phenol>

: 74-88-4
methyl iodide

: 159390-40-6
1,1'-Methylenebis<6-bromo-3-(1,1-dimethylethyl)-2-methoxybenzene>

Guidance literature:: With 18-crown-6 ether; potassium hydride; In N,N-dimethyl-formamide; 1.) 0 deg C, 1 h; 25 deg C, 1 h, 2.) 70 deg C, 12 h;
DOI:10.1021/jo00104a040