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4-(α-methyl-α-hydroxy-p-bromobenzyl)-2-chloroquinazoline

Base Information
  • Chemical Name:4-(α-methyl-α-hydroxy-p-bromobenzyl)-2-chloroquinazoline
  • CAS No.:204520-39-8
  • Molecular Formula:C16H12BrClN2O
  • Molecular Weight:363.641
  • Hs Code.:
4-(α-methyl-α-hydroxy-p-bromobenzyl)-2-chloroquinazoline

Synonyms:4-(α-methyl-α-hydroxy-p-bromobenzyl)-2-chloroquinazoline

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Chemical Property of 4-(α-methyl-α-hydroxy-p-bromobenzyl)-2-chloroquinazoline
Chemical Property:
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MSDS Files:

SDS file from LookChem

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Technology Process of 4-(α-methyl-α-hydroxy-p-bromobenzyl)-2-chloroquinazoline

There total 2 articles about 4-(α-methyl-α-hydroxy-p-bromobenzyl)-2-chloroquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
Multi-step reaction with 2 steps
1: 79 percent / NaH, 1,3-dimethylimidazolium iodide / tetrahydrofuran / 5 h / Heating
2: 64 percent / diethyl ether; tetrahydrofuran / 1 h / Ambient temperature
With sodium hydride; 1,3-dimethylimidazolim iodide; In tetrahydrofuran; diethyl ether;
DOI:10.1248/cpb.46.199
Guidance literature:
Multi-step reaction with 2 steps
1: 79 percent / NaH, 1,3-dimethylimidazolium iodide / tetrahydrofuran / 5 h / Heating
2: 64 percent / diethyl ether; tetrahydrofuran / 1 h / Ambient temperature
With sodium hydride; 1,3-dimethylimidazolim iodide; In tetrahydrofuran; diethyl ether;
DOI:10.1248/cpb.46.199
Guidance literature:
With tetra-n-butylammonium cyanide; In tetrahydrofuran; for 2.5h; Heating;
DOI:10.1248/cpb.46.199
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