5,8-Difluoro-1,4-benzodioxane

Base Information

Chemical Name:5,8-Difluoro-1,4-benzodioxane
CAS No.:72912-50-6
Molecular Formula:C8H6 F2 O2
Molecular Weight:172.13
Hs Code.:2932999099
DSSTox Substance ID:DTXSID90403566
Wikidata:Q82207264
Mol file:72912-50-6.mol

Synonyms:72912-50-6;5,8-difluoro-1,4-benzodioxane;5,8-DIFLUORO-1,4-BENZODIOXAN;5,8-DIFLUORO-1,4-BENZODIXAN);SCHEMBL197752;DTXSID90403566;VNPXSBILOLAXAT-UHFFFAOYSA-N;AKOS024055768;5,8-Difluoro-1,4-benzodioxan, 99%;InChI=1/C8H6F2O2/c9-5-1-2-6(10)8-7(5)11-3-4-12-8/h1-2H,3-4H

Suppliers and Price of 5,8-Difluoro-1,4-benzodioxane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 5,8-Difluoro-1,4-benzodioxane

Chemical Property:

Vapor Pressure:0.585mmHg at 25°C
Refractive Index:1.495
Boiling Point:195.5°C at 760 mmHg
Flash Point:78.5°C
PSA：18.46000
Density:1.357g/cm³
LogP:1.73600
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:172.03358575
Heavy Atom Count:12
Complexity:147

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2=C(C=CC(=C2O1)F)F

Technology Process of 5,8-Difluoro-1,4-benzodioxane

There total 2 articles about 5,8-Difluoro-1,4-benzodioxane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 72912-49-3
2-(2,3,6-trifluorophenoxy)ethanol

: 72912-50-6
5,8-difluoro-2,3-dihydro-1,4-benzodioxin

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; Heating;
DOI:10.1021/jo00314a054

Reference yield:

: 551-62-2
1,2,3,4-tetrafluorobenzene

: 72912-50-6
5,8-difluoro-2,3-dihydro-1,4-benzodioxin

Guidance literature:: Multi-step reaction with 2 steps

1: 42 percent / NaOH / 3.5 h / Heating

2: 42 percent / K₂CO₃ / dimethylformamide / Heating

With sodium hydroxide; potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1021/jo00314a054