benzyl((2S,3S)-1-(2,4-dimethoxybenzyl)-2-(hydroxymethyl)-4-oxoazetidin-3-yl)carbamate

Base Information

Chemical Name:benzyl((2S,3S)-1-(2,4-dimethoxybenzyl)-2-(hydroxymethyl)-4-oxoazetidin-3-yl)carbamate
CAS No.:86334-63-6
Molecular Formula:C₂₁H₂₄N₂O₆
Molecular Weight:400.431
Hs Code.:
Mol file:86334-63-6.mol

Synonyms:(3S,4S)-3-(benzyloxycarboxamido)-1-(2,4-dimethoxybenzyl)-4-(hydroxymethyl)-2-azetidinone

Suppliers and Price of benzyl((2S,3S)-1-(2,4-dimethoxybenzyl)-2-(hydroxymethyl)-4-oxoazetidin-3-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 7 raw suppliers

Chemical Property of benzyl((2S,3S)-1-(2,4-dimethoxybenzyl)-2-(hydroxymethyl)-4-oxoazetidin-3-yl)carbamate

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

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Technology Process of benzyl((2S,3S)-1-(2,4-dimethoxybenzyl)-2-(hydroxymethyl)-4-oxoazetidin-3-yl)carbamate

There total 11 articles about benzyl((2S,3S)-1-(2,4-dimethoxybenzyl)-2-(hydroxymethyl)-4-oxoazetidin-3-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 86299-41-4
(3S,4S)-3-(benzyloxycarboxamido)-1-(2,4-dimethoxybenzyl)-4-formyl-2-azetidinone

: 86334-63-6
(3S,4S)-3-(benzyloxycarboxamido)-1-(2,4-dimethoxybenzyl)-4-(hydroxymethyl)-2-azetidinone

Guidance literature:: With methanol; sodium tetrahydroborate; In dichloromethane; at 0 ℃; for 2h;

Reference yield:

: 86299-39-0
N-[(3S,4S)-cis-1-(2,4-dimethoxybenzyl)-4-formyl-2-oxo-3-azetidinyl]phthalimide

: 501-53-1,94274-21-2
benzyl chloroformate

: 86334-63-6
(3S,4S)-3-(benzyloxycarboxamido)-1-(2,4-dimethoxybenzyl)-4-(hydroxymethyl)-2-azetidinone

Guidance literature:: With sodium cyanoborohydride; sodium hydrogencarbonate; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water; acetic acid;

Reference yield:

: 20781-20-8
2,4-Dimethoxybenzylamine

: 86334-63-6
(3S,4S)-3-(benzyloxycarboxamido)-1-(2,4-dimethoxybenzyl)-4-(hydroxymethyl)-2-azetidinone

Guidance literature:: Multi-step reaction with 7 steps

1: magnesium sulfate / dichloromethane / 2.33 h / 0 - 20 °C

2: triethylamine / dichloromethane / 16.5 h / 0 - 20 °C

3: hydrazine hydrate / ethanol / 3.33 h / Reflux

4: sodium hydrogencarbonate / ethyl acetate / 3 h / 0 - 20 °C

5: water; toluene-4-sulfonic acid / tetrahydrofuran / 16 h / 70 °C

6: sodium periodate / water; ethyl acetate / 2 h / 50 °C

7: methanol; sodium tetrahydroborate / dichloromethane / 2 h / 0 °C

With methanol; sodium tetrahydroborate; sodium periodate; water; sodium hydrogencarbonate; magnesium sulfate; toluene-4-sulfonic acid; hydrazine hydrate; triethylamine; In tetrahydrofuran; ethanol; dichloromethane; water; ethyl acetate;