1-Ethoxy-2-methoxy-4-[(E)-2-((E)-2-phenyl-ethenesulfonyl)-vinyl]-benzene

Base Information

• Chemical Name: 1-Ethoxy-2-methoxy-4-[(E)-2-((E)-2-phenyl-ethenesulfonyl)-vinyl]-benzene
• CAS No.: 137325-93-0
• Molecular Formula: C₁₉H₂₀O₄S
• Molecular Weight: 344.431
• Mol file: 137325-93-0.mol

Synonyms:1-Ethoxy-2-methoxy-4-[(E)-2-((E)-2-phenyl-ethenesulfonyl)-vinyl]-benzene

Chemical Property of 1-Ethoxy-2-methoxy-4-[(E)-2-((E)-2-phenyl-ethenesulfonyl)-vinyl]-benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Ethoxy-2-methoxy-4-[(E)-2-((E)-2-phenyl-ethenesulfonyl)-vinyl]-benzene

There total 3 articles about 1-Ethoxy-2-methoxy-4-[(E)-2-((E)-2-phenyl-ethenesulfonyl)-vinyl]-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

(Z)-styrylsulfonyl acetic acid (137325-91-8,102154-41-6) + 4-ethoxy-3-methoxybenzaldehyde (120-25-2) → 1-Ethoxy-2-methoxy-4-[(E)-2-((E)-2-phenyl-ethenesulfonyl)-vinyl]-benzene (137325-93-0)

Guidance literature:

With acetic acid; benzylamine; for 3h; Heating;

Reference yield:

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) → 1-Ethoxy-2-methoxy-4-[(E)-2-((E)-2-phenyl-ethenesulfonyl)-vinyl]-benzene (137325-93-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 79 percent / SO₂Cl₂; N-methylpyrrolidine / 4 h / 90 °C

2.1: NaHCO₃; Na₂SO₃ / H₂O / 1 h / 80 - 90 °C

2.2: 63 percent / H₂O / 3 h / pH 10 / Heating

3.1: 83 percent / benzylamine; glacial acetic acid / 3 h / Heating

With 1-Methylpyrrolidine; sulfuryl dichloride; sodium hydrogencarbonate; acetic acid; benzylamine; sodium sulfite; In water; 1.1: Substitution / 2.1: Substitution / 2.2: Alkylation / 3.1: Knoevenagel condensation;

Reference yield:

trans 2-phenylethenesulfonyl chloride (52147-97-4) → 1-Ethoxy-2-methoxy-4-[(E)-2-((E)-2-phenyl-ethenesulfonyl)-vinyl]-benzene (137325-93-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: NaHCO₃; Na₂SO₃ / H₂O / 1 h / 80 - 90 °C

1.2: 63 percent / H₂O / 3 h / pH 10 / Heating

2.1: 83 percent / benzylamine; glacial acetic acid / 3 h / Heating

With sodium hydrogencarbonate; acetic acid; benzylamine; sodium sulfite; In water; 1.1: Substitution / 1.2: Alkylation / 2.1: Knoevenagel condensation;

upstream raw materials:

(Z)-styrylsulfonyl acetic acid

4-ethoxy-3-methoxybenzaldehyde

styrene

trans 2-phenylethenesulfonyl chloride