3-METHOXY-2,2-DIMETHYLPROPYLAMINE

Base Information

• Chemical Name: 3-METHOXY-2,2-DIMETHYLPROPYLAMINE
• CAS No.: 767264-22-2
• Molecular Formula: C₆H₁₅NO
• Molecular Weight: 117.191
• Hs Code.: 2922199090
• Mol file: 767264-22-2.mol

Synonyms:3-METHOXY-2,2-DIMETHYLPROPYLAMINE

Chemical Property of 3-METHOXY-2,2-DIMETHYLPROPYLAMINE

Chemical Property:

• Vapor Pressure: 3.49mmHg at 25°C
• Refractive Index: 1.423
• Boiling Point: 152.4°C at 760 mmHg
• Flash Point: 39.9°C
• PSA: 35.25000
• Density: 0.851g/cm³
• LogP: 1.31800

Purity/Quality:

98%min ^*data from raw suppliers

(3-methoxy-2,2-dimethylpropyl)aminehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-METHOXY-2,2-DIMETHYLPROPYLAMINE

There total 1 articles about 3-METHOXY-2,2-DIMETHYLPROPYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

3-methoxy-2,2-dimethylpropanenitrile (99705-29-0) → 3-methoxy-2,2-dimethylpropylamine (767264-22-2)

Guidance literature:

With hydrogen; Raney Nickel; In ethanol; water; at 50 ℃; for 3h; under 3800.26 Torr;

Reference yield:

3-methoxy-2,2-dimethylpropylamine (767264-22-2) + 5-cyano-1-(3-trifluoromethoxybenzyl)-1H-indole-2-carboxylic acid (911060-78-1) → 5-cyano-1-(3-trifluoromethoxybenzyl)-1H-indole-2-carboxylic acid-(3-methoxy-2,2-dimethylpropyl)amide

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃;

DOI:10.1016/j.bmcl.2010.10.104

upstream raw materials:

3-methoxy-2,2-dimethylpropanenitrile

Refernces

• 1、 -. "1-BENZYLINDOLE-2-CARBOXAMIDE DERIVATIVES". Page/Page column 54. . Retrieved 2010/11/24.