(1R,2R)-N-Boc-1-amino-2-indanol

Base Information

Chemical Name:(1R,2R)-N-Boc-1-amino-2-indanol
CAS No.:766556-66-5
Molecular Formula:C14H19 N O3
Molecular Weight:249.31
Hs Code.:2924299090
DSSTox Substance ID:DTXSID70592124
Wikidata:Q82486055
Mol file:766556-66-5.mol

Synonyms:766556-66-5;(1R,2R)-N-BOC-1-AMINO-2-INDANOL;Tert-butyl N-[(1R,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamate;tert-Butyl ((1R,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)carbamate;rel-tert-Butyl ((1R,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)carbamate;438051-09-3;tert-Butyl [(1R,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamate;SCHEMBL56008;DTXSID70592124;ROUONLKDWVQKNB-VXGBXAGGSA-N;(1R,2R)-N-Boc-1-amino-2-indanol, AldrichCPR;EN300-6882488;tert-butyl[(1R,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamate

Suppliers and Price of (1R,2R)-N-Boc-1-amino-2-indanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (1R,2R)-N-Boc-1-amino-2-indanol

Chemical Property:

PSA：58.56000
LogP:2.56030
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:249.13649347
Heavy Atom Count:18
Complexity:311

Purity/Quality:

Safty Information:

Pictogram(s): T
Hazard Codes:T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1C(CC2=CC=CC=C12)O
Isomeric SMILES:CC(C)(C)OC(=O)N[C@H]1[C@@H](CC2=CC=CC=C12)O

Technology Process of (1R,2R)-N-Boc-1-amino-2-indanol

There total 1 articles about (1R,2R)-N-Boc-1-amino-2-indanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: trans-1-aminoindan-2-ol

: 438051-03-7
tert-butyl ((1S,2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)carbamate

: 766556-66-5
tert-butyl [(1R,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-carbamate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 12h; Title compound not separated from byproducts.;
DOI:10.1039/b108538g

Reference yield: 81.0%

: 367-86-2
1-fluoro-2-nitro-4-trifluoromethyl-benzene

: 766556-66-5
tert-butyl [(1R,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-carbamate

: 1402743-80-9
tert-butyl ((1R,2R)-2-(2-nitro-4-(trifluoromethyl)phenoxy)-2,3-dihydro-1H-inden-1-yl)carbamate

Guidance literature:: With lithium hexamethyldisilazane; In tetrahydrofuran; at -40 - 20 ℃;
DOI:10.1002/anie.201203852

Reference yield: 69.0%

: 603-33-8
triphenylbismuthane

: 766556-66-5
tert-butyl [(1R,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-carbamate

: tert-butyl ((1R,2R)-2-phenoxy-2,3-dihydro-1H-inden-1-yl)carbamate

Guidance literature:: With pyridine; oxygen; copper diacetate; In dichloromethane; at 50 ℃; Sealed tube; Inert atmosphere;
DOI:10.1039/c4ob02497d