methyl N-tert-butoxycarbonyl-N'-(p-methoxybenzyl)-(S)-alanyl-(S)-tryptophanate

Base Information

Chemical Name:methyl N-tert-butoxycarbonyl-N'-(p-methoxybenzyl)-(S)-alanyl-(S)-tryptophanate
CAS No.:300766-76-1
Molecular Formula:C₂₈H₃₅N₃O₆
Molecular Weight:509.602
Hs Code.:

Synonyms:methyl N-tert-butoxycarbonyl-N'-(p-methoxybenzyl)-(S)-alanyl-(S)-tryptophanate

Suppliers and Price of methyl N-tert-butoxycarbonyl-N'-(p-methoxybenzyl)-(S)-alanyl-(S)-tryptophanate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl N-tert-butoxycarbonyl-N'-(p-methoxybenzyl)-(S)-alanyl-(S)-tryptophanate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl N-tert-butoxycarbonyl-N'-(p-methoxybenzyl)-(S)-alanyl-(S)-tryptophanate

There total 4 articles about methyl N-tert-butoxycarbonyl-N'-(p-methoxybenzyl)-(S)-alanyl-(S)-tryptophanate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 15761-38-3
L-N-Boc-Ala

: 168766-62-9
methyl 3-(1H-indol-3-yl)-2-(4-methoxybenzylamino)propanoate

: 300766-76-1
methyl N-tert-butoxycarbonyl-N'-(p-methoxybenzyl)-(S)-alanyl-(S)-tryptophanate

Guidance literature:: With dicyclohexyl-carbodiimide; In tetrahydrofuran; at 80 ℃; for 24h;
DOI:10.3987/com-00-8942

Reference yield:

: 123-11-5
4-methoxy-benzaldehyde

: 300766-76-1
methyl N-tert-butoxycarbonyl-N'-(p-methoxybenzyl)-(S)-alanyl-(S)-tryptophanate

Guidance literature:: Multi-step reaction with 3 steps

1: benzene / 20.25 h / 0 - 20 °C

2: 948 mg / H₂ / Pd/C / methanol / 2 h / 2172.02 Torr

3: 79 percent / DCC / tetrahydrofuran / 24 h / 80 °C

With hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In tetrahydrofuran; methanol; benzene; 1: Condensation / 2: Catalytic hydrogenation / 3: Acylation;
DOI:10.3987/com-00-8942

Reference yield:

: (S)-3-(1H-Indol-3-yl)-2-{[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-amino}-propionic acid methyl ester

: 300766-76-1
methyl N-tert-butoxycarbonyl-N'-(p-methoxybenzyl)-(S)-alanyl-(S)-tryptophanate

Guidance literature:: Multi-step reaction with 2 steps

1: 948 mg / H₂ / Pd/C / methanol / 2 h / 2172.02 Torr

2: 79 percent / DCC / tetrahydrofuran / 24 h / 80 °C

With hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In tetrahydrofuran; methanol; 1: Catalytic hydrogenation / 2: Acylation;
DOI:10.3987/com-00-8942