5-ethyl>amino>-2,4-dinitrobenzamide

Base Information

• Chemical Name: 5-ethyl>amino>-2,4-dinitrobenzamide
• CAS No.: 156423-10-8
• Molecular Formula: C₁₇H₂₈N₄O₇Si
• Molecular Weight: 428.517
• Mol file: 156423-10-8.mol

Synonyms:5-ethyl>amino>-2,4-dinitrobenzamide

Chemical Property of 5-ethyl>amino>-2,4-dinitrobenzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-ethyl>amino>-2,4-dinitrobenzamide

There total 1 articles about 5-ethyl>amino>-2,4-dinitrobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

tert-butyldimethylsilyl chloride (18162-48-6) + 5--2,4-dinitrobenzamide (142439-58-5) → 5-ethyl>amino>-2,4-dinitrobenzamide (156423-10-8) + 5-ethyl>amino>-2,4-dinitrobenzamide

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 18h;

DOI:10.1021/jm00040a009

Reference yield:

methanesulfonyl chloride (124-63-0) + 5-ethyl>amino>-2,4-dinitrobenzamide (156423-10-8) → Methanesulfonic acid 2-[[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-(5-carbamoyl-2,4-dinitro-phenyl)-amino]-ethyl ester (1026671-07-7)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 0.166667h;

DOI:10.1021/jm00040a009

Reference yield:

5-ethyl>amino>-2,4-dinitrobenzamide (156423-10-8) → 5--2,4-dinitrobenzamide (156423-12-0)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂ / 0.17 h / 20 °C

2: LiCl / dimethylformamide / 0.33 h / 125 °C

With triethylamine; lithium chloride; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jm00040a009

upstream raw materials:

tert-butyldimethylsilyl chloride

5--2,4-dinitrobenzamide

Downstream raw materials:

Methanesulfonic acid 2-[[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-(5-carbamoyl-2,4-dinitro-phenyl)-amino]-ethyl ester

5--2,4-dinitrobenzamide

2-[5-(aminocarbonyl)-N-(2-chloroethyl)-2,4-dinitroanilino]ethyl methanesulfonate