N-(2-(tert-butylamino)-1-(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)-2-oxoethyl)-N-(4-methoxybenzyl)but-2-ynamide

Base Information

• Chemical Name: N-(2-(tert-butylamino)-1-(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)-2-oxoethyl)-N-(4-methoxybenzyl)but-2-ynamide
• CAS No.: 1410884-68-2
• Molecular Formula: C₂₅H₂₉N₃O₃S
• Molecular Weight: 451.59

Synonyms:N-(2-(tert-butylamino)-1-(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)-2-oxoethyl)-N-(4-methoxybenzyl)but-2-ynamide

Chemical Property of N-(2-(tert-butylamino)-1-(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)-2-oxoethyl)-N-(4-methoxybenzyl)but-2-ynamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-(tert-butylamino)-1-(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)-2-oxoethyl)-N-(4-methoxybenzyl)but-2-ynamide

There total 1 articles about N-(2-(tert-butylamino)-1-(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)-2-oxoethyl)-N-(4-methoxybenzyl)but-2-ynamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2-Butynoic acid (590-93-2) + tert-butylisonitrile (119072-55-8,7188-38-7) + 4-methyl-4H-thieno[3,2-b]pyrrole-5-carbaldehyde (121933-60-6) + 4-methoxy-benzylamine (2393-23-9) → N-(2-(tert-butylamino)-1-(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)-2-oxoethyl)-N-(4-methoxybenzyl)but-2-ynamide (1410884-68-2)

Guidance literature:

With sodium sulfate; In methanol; at 50 ℃; for 48h;

DOI:10.1039/c2cc35900f

Reference yield: 86.0%

N-(2-(tert-butylamino)-1-(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)-2-oxoethyl)-N-(4-methoxybenzyl)but-2-ynamide (1410884-68-2) → (E)-N-(tert-butyl)-8-ethylidene-6-(4-methoxybenzyl)-4-methyl-7-oxo-5,6,7,8-tetrahydro-4H-thieno[2',3':4,5]pyrrolo[2,3-c]pyridine-5-carboxamide (1410884-87-5)

Guidance literature:

With triphenylphosphinegold(I) triflate; In chloroform-d1; at 50 ℃; for 3h; regioselective reaction;

DOI:10.1039/c2cc35900f

Reference yield: 79.0%

N-(2-(tert-butylamino)-1-(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)-2-oxoethyl)-N-(4-methoxybenzyl)but-2-ynamide (1410884-68-2) → N-(tert-butyl)-6-(4-methoxybenzyl)-4,9-dimethyl-7-oxo-4,5,6,7-tetrahydrothieno[2',3':4,5]pyrrolo[2,3-c]azepine-5-carboxamide (1410885-04-9)

Guidance literature:

With platinum(II) chloride; In chloroform-d1; at 50 ℃; for 14h; regioselective reaction;

DOI:10.1039/c2cc35900f

upstream raw materials:

2-Butynoic acid

tert-butylisonitrile

4-methyl-4H-thieno[3,2-b]pyrrole-5-carbaldehyde

4-methoxy-benzylamine

Downstream raw materials:

(E)-N-(tert-butyl)-8-ethylidene-6-(4-methoxybenzyl)-4-methyl-7-oxo-5,6,7,8-tetrahydro-4H-thieno[2',3':4,5]pyrrolo[2,3-c]pyridine-5-carboxamide

N-(tert-butyl)-6-(4-methoxybenzyl)-4,9-dimethyl-7-oxo-4,5,6,7-tetrahydrothieno[2',3':4,5]pyrrolo[2,3-c]azepine-5-carboxamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1410884-68-2 N-(2-(tert-butylamino)-1-(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)-2-oxoethyl)-N-(4-methoxybenzyl)but-2-ynamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send