(4R)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid

Base Information

Chemical Name:(4R)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
CAS No.:72778-00-8
Molecular Formula:C6H11 N O2 S
Molecular Weight:161.225
Hs Code.:2934999090
European Community (EC) Number:623-292-7
DSSTox Substance ID:DTXSID20420827
Nikkaji Number:J1.452.703F
Wikidata:Q27447757
ChEMBL ID:CHEMBL1229504
Mol file:72778-00-8.mol

Synonyms:72778-00-8;L-5,5-Dimethylthiazolidine-4-carboxylic acid;(R)-5,5-Dimethylthiazolidine-4-carboxylic acid;(4R)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid;3,3-Dimethyl-4-thiaproline;(R)-4-Carboxy-5,5-dimethylthiazolidine;SCHEMBL950964;CHEMBL1229504;DTXSID20420827;MFCD00070264;AKOS006272974;AS-67222;(R)-5,5-Dimethyl-4-thiazolidinecarboxylic Acid;(R)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid;Q27447757

Suppliers and Price of (4R)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
L-5,5-Dimethylthiazolidine-4-carboxylic Acid
500mg
$ 403.00

TRC
L-5,5-Dimethylthiazolidine-4-carboxylic acid
1g
$ 195.00

Sigma-Aldrich
L-5,5-Dimethylthiazolidine-4-carboxylic acid
1g
$ 294.00

Medical Isotopes, Inc.
L-5,5-Dimethylthiazolidine-4-carboxylic acid
500 mg
$ 845.00

Crysdot
(R)-5,5-Dimethylthiazolidine-4-carboxylicacid 97%
10g
$ 352.00

Chem-Impex
(R)-5,5-dimethyl-1,3-thiazolidine-4-carboxylicacid,≥99%(HPLC) ≥99%(HPLC)
25G
$ 1700.61

Chem-Impex
(R)-5,5-dimethyl-1,3-thiazolidine-4-carboxylicacid,99%(HPLC) 99%(HPLC)
5G
$ 336.00

Chem-Impex
(R)-5,5-dimethyl-1,3-thiazolidine-4-carboxylicacid,≥99%(HPLC) ≥99%(HPLC)
1G
$ 87.36

Chemenu
(R)-5,5-Dimethylthiazolidine-4-carboxylicacid 97%
10g
$ 332.00

Chemenu
(R)-5,5-Dimethylthiazolidine-4-carboxylicacid 97%
25g
$ 634.00

Total 11 raw suppliers

Chemical Property of (4R)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid

Chemical Property:

Melting Point:206°C dec.
Refractive Index:[a]20D = - 149 ± 2 o (C=1 in water)
PSA：74.63000
LogP:0.84090
Storage Temp.:2-8°C
Solubility.:Dichloromethane, DMSO, Methanol
XLogP3:-1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:161.05104977
Heavy Atom Count:10
Complexity:158

Purity/Quality:

97% ^*data from raw suppliers

L-5,5-Dimethylthiazolidine-4-carboxylic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C(NCS1)C(=O)O)C
Isomeric SMILES:CC1([C@H](NCS1)C(=O)O)C
Uses Found to act on the cell membrane of tumour cells, possible causing a reverse transformation to normal cells through restoration of contact inhibition.

Technology Process of (4R)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid

There total 4 articles about (4R)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 1113-41-3
L-penicillamine

: 72778-00-8
(R)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid

Guidance literature:: With pyridine; In ethanol; water; at 110 ℃; for 0.0833333h; Microwave irradiation;
DOI:10.1016/j.bmc.2009.06.065

Reference yield: 80.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 1113-41-3
L-penicillamine

: 72778-00-8
5,5-dimethylthiazolidine-4-carboxylic acid

Guidance literature:: With pyridine; In water; a) water (pH 5), several h, b) 0 deg C, 3 h, c) ethanol, 0 deg C, overnight;
DOI:10.1021/jm00122a030