(S)-2-methyl-N-((S)-1,1,1-trifluoro-2-(4-methoxyphenyl)-4-oxo-4-phenylbutan-2-yl)propane-2-sulfinamide

Base Information

Chemical Name:(S)-2-methyl-N-((S)-1,1,1-trifluoro-2-(4-methoxyphenyl)-4-oxo-4-phenylbutan-2-yl)propane-2-sulfinamide
CAS No.:1381765-60-1
Molecular Formula:C₂₁H₂₄F₃NO₃S
Molecular Weight:427.488
Hs Code.:

Synonyms:(S)-2-methyl-N-((S)-1,1,1-trifluoro-2-(4-methoxyphenyl)-4-oxo-4-phenylbutan-2-yl)propane-2-sulfinamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-2-methyl-N-((S)-1,1,1-trifluoro-2-(4-methoxyphenyl)-4-oxo-4-phenylbutan-2-yl)propane-2-sulfinamide

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Technology Process of (S)-2-methyl-N-((S)-1,1,1-trifluoro-2-(4-methoxyphenyl)-4-oxo-4-phenylbutan-2-yl)propane-2-sulfinamide

There total 1 articles about (S)-2-methyl-N-((S)-1,1,1-trifluoro-2-(4-methoxyphenyl)-4-oxo-4-phenylbutan-2-yl)propane-2-sulfinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 884595-98-6
C₁₃H₁₆F₃NO₂S

: 98-86-2
acetophenone

: 1381765-61-2
(S)-2-methyl-N-((R)-1,1,1-trifluoro-2-(4-methoxyphenyl)-4-oxo-4-phenylbutan-2-yl)propane-2-sulfinamide

: 1381765-60-1
(S)-2-methyl-N-((S)-1,1,1-trifluoro-2-(4-methoxyphenyl)-4-oxo-4-phenylbutan-2-yl)propane-2-sulfinamide

Guidance literature:: C₁₃H₁₆F₃NO₂S; acetophenone; With lithium diisopropyl amide; In tetrahydrofuran; n-heptane; ethylbenzene; at -78 ℃; for 4h;

With ammonium chloride; In tetrahydrofuran; n-heptane; ethylbenzene; water; optical yield given as %de; diastereoselective reaction;
DOI:10.1016/j.tet.2012.04.070