1,2-dihydro-1-<2-(3-methoxyphenyl)ethyl>cyclobutabenzen-1-ol

Base Information

• Chemical Name: 1,2-dihydro-1-<2-(3-methoxyphenyl)ethyl>cyclobutabenzen-1-ol
• CAS No.: 121119-85-5
• Molecular Formula: C₁₇H₁₈O₂
• Molecular Weight: 254.329
• Mol file: 121119-85-5.mol

Synonyms:1,2-dihydro-1-<2-(3-methoxyphenyl)ethyl>cyclobutabenzen-1-ol

Chemical Property of 1,2-dihydro-1-<2-(3-methoxyphenyl)ethyl>cyclobutabenzen-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-dihydro-1-<2-(3-methoxyphenyl)ethyl>cyclobutabenzen-1-ol

There total 1 articles about 1,2-dihydro-1-<2-(3-methoxyphenyl)ethyl>cyclobutabenzen-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzocyclobutenone (3469-06-5) + 1-(2-chloroethyl)-3-methoxybenzene (73004-96-3) → 1,2-dihydro-1-<2-(3-methoxyphenyl)ethyl>cyclobutabenzen-1-ol (121119-85-5)

Guidance literature:

With magnesium; multistep reaction; other alkylaryl halide;

DOI:10.1002/hlca.19890720112

Reference yield:

1,2-dihydro-1-<2-(3-methoxyphenyl)ethyl>cyclobutabenzen-1-ol (121119-85-5) → 2-<2-(3-methoxyphenyl)ethyl>-1H-indole

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) HN₃, 2.) BF₃*Et₂O / 1.) benzene, 5 deg C, 2.) 5 deg C, 20 min

2: 89.5 percent / 1.) 96 percent H₂SO₄, 2.) 2 M aq. NH₃ / CHCl₃ / 0.67 h / 0 °C

With ammonium hydroxide; tris-(2-chloro-ethyl)-amine; sulfuric acid; boron trifluoride diethyl etherate; In chloroform;

DOI:10.1002/hlca.19890720112

Reference yield:

1,2-dihydro-1-<2-(3-methoxyphenyl)ethyl>cyclobutabenzen-1-ol (121119-85-5) → 1-azido-1,2-dihydro-1-<2-(3-methoxyphenyl)ethyl>cyclobutabenzene

Guidance literature:

With tris-(2-chloro-ethyl)-amine; boron trifluoride diethyl etherate; Yield given. Multistep reaction; 1.) benzene, 5 deg C, 2.) 5 deg C, 20 min;

DOI:10.1002/hlca.19890720112

upstream raw materials:

benzocyclobutenone

1-(2-chloroethyl)-3-methoxybenzene