5-AMINO-2-PYRIDINEETHIONE

Base Information

• Chemical Name: 5-AMINO-2-PYRIDINEETHIONE
• CAS No.: 760117-50-8
• Molecular Formula: C₅H₆N₂S
• Molecular Weight: 126.182
• Mol file: 760117-50-8.mol

Synonyms:5-AMINO-2-PYRIDINEETHIONE;2-Pyridinethiol,5-amino-(9CI)

Chemical Property of 5-AMINO-2-PYRIDINEETHIONE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.677
• Boiling Point: 333.09°C at 760 mmHg
• Flash Point: 155.247°C
• PSA: 73.90000
• Density: 1.294g/cm³
• LogP: 1.90760

Purity/Quality:

98%min ^*data from raw suppliers

5-AMINO-2-PYRIDINEETHIONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-AMINO-2-PYRIDINEETHIONE

There total 3 articles about 5-AMINO-2-PYRIDINEETHIONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2-mercapto-5-nitropyridine (2127-09-5) → 5-amino-2-thiolpyridine (27885-56-9,760117-50-8)

Guidance literature:

With water; tin(ll) chloride;

Reference yield: 30.0%

5,5'-dinitro-2,2'-disulfanediyl-bis-pyridine (2127-10-8) → 5-amino-2-thiolpyridine (27885-56-9,760117-50-8)

Guidance literature:

With sodium citrate; titanium(III) chloride; In ethanol; water; acetic acid; pH 4.5 to 6.O;

Reference yield:

2-chloro-5-nitropyridine (4548-45-2) → 5-amino-2-thiolpyridine (27885-56-9,760117-50-8)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol; potassium hydrogensulfide

2: SnCl₂; aqueous HCl

With hydrogenchloride; methanol; potassium hydrosulfide; tin(ll) chloride;

upstream raw materials:

2-mercapto-5-nitropyridine

5,5'-dinitro-2,2'-disulfanediyl-bis-pyridine

2-chloro-5-nitropyridine

Refernces

• 1、 Delarge,Thunus,Beckers,et al.. "Studies of thiaheterocyclic derivatives. I. Synthesis and pharmacological screening". . p. 559 - 565. Retrieved 2007/10/02.