10-Bromo-decanoic acid (2-{2-[(10-bromo-decanoyl)-methyl-amino]-phenyldisulfanyl}-phenyl)-methyl-amide

Base Information

• Chemical Name: 10-Bromo-decanoic acid (2-{2-[(10-bromo-decanoyl)-methyl-amino]-phenyldisulfanyl}-phenyl)-methyl-amide
• CAS No.: 78082-12-9
• Molecular Formula: C₃₄H₅₀Br₂N₂O₂S₂
• Molecular Weight: 742.723
• Mol file: 78082-12-9.mol

Synonyms:10-Bromo-decanoic acid (2-{2-[(10-bromo-decanoyl)-methyl-amino]-phenyldisulfanyl}-phenyl)-methyl-amide

Chemical Property of 10-Bromo-decanoic acid (2-{2-[(10-bromo-decanoyl)-methyl-amino]-phenyldisulfanyl}-phenyl)-methyl-amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 10-Bromo-decanoic acid (2-{2-[(10-bromo-decanoyl)-methyl-amino]-phenyldisulfanyl}-phenyl)-methyl-amide

There total 8 articles about 10-Bromo-decanoic acid (2-{2-[(10-bromo-decanoyl)-methyl-amino]-phenyldisulfanyl}-phenyl)-methyl-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.2%

2,2'-dithiobis(N-methylaniline) (3495-63-4) + 10-bromodecanoyl chloride (73674-11-0) → 10-Bromo-decanoic acid (2-{2-[(10-bromo-decanoyl)-methyl-amino]-phenyldisulfanyl}-phenyl)-methyl-amide (78082-12-9)

Guidance literature:

With triethylamine; In diethyl ether; for 0.5h; Ambient temperature;

Reference yield:

2-(2-Methylamino-phenylsulfinyl)-11-methyl-cycloundecanon (73674-30-3) → 10-Bromo-decanoic acid (2-{2-[(10-bromo-decanoyl)-methyl-amino]-phenyldisulfanyl}-phenyl)-methyl-amide (78082-12-9)

Guidance literature:

Multi-step reaction with 2 steps

1: xylene / 2 h / 100 °C

2: 98.2 percent / Et₃N / diethyl ether / 0.5 h / Ambient temperature

With triethylamine; In diethyl ether; xylene;

Reference yield:

15,17-Dimethyl-6,7,8,9,10,11,12,13,14,15-decahydro-17H-5-thia-17-aza-benzocyclopentadecen-16-one (77922-74-8) → 10-Bromo-decanoic acid (2-{2-[(10-bromo-decanoyl)-methyl-amino]-phenyldisulfanyl}-phenyl)-methyl-amide (78082-12-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 94 percent / NaIO₄ / H₂O; methanol / 20 h / Ambient temperature

2: LDA / tetrahydrofuran / 1.) -78 deg C, 30 min, 2.) 30 min, ice bath

3: xylene / 2 h / 100 °C

4: 98.2 percent / Et₃N / diethyl ether / 0.5 h / Ambient temperature

With sodium periodate; triethylamine; lithium diisopropyl amide; In tetrahydrofuran; methanol; diethyl ether; water; xylene;

upstream raw materials:

2,2'-dithiobis(N-methylaniline)

10-bromodecanoyl chloride

2-(2-Methylamino-phenylsulfinyl)-11-methyl-cycloundecanon

15,17-Dimethyl-6,7,8,9,10,11,12,13,14,15-decahydro-17H-5-thia-17-aza-benzocyclopentadecen-16-one

Downstream raw materials:

cyclodecanone

2-(2-Methylamino-phenylsulfinyl)-10-methyl-cyclodecanon

2-(2-Methylamino-phenylsulfonyl)-cyclodecanon

cyclodecanone-(2,4-dinitro-phenylhydrazone)