2-Amino-4-ethoxypyrimidine-5-carboxylic acid

Base Information

Chemical Name:2-Amino-4-ethoxypyrimidine-5-carboxylic acid
CAS No.:72411-91-7
Molecular Formula:C₇H₉N₃O₃
Molecular Weight:183.167
Hs Code.:
DSSTox Substance ID:DTXSID50510927
Wikidata:Q82369489
Mol file:72411-91-7.mol

Synonyms:72411-91-7;2-Amino-4-ethoxypyrimidine-5-carboxylic acid;DTXSID50510927;2-Amino-4-ethoxypyrimidine-5-carboxylicacid;EN300-7465439

Suppliers and Price of 2-Amino-4-ethoxypyrimidine-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-Amino-4-ethoxypyrimidine-5-carboxylic acid

Chemical Property:

PSA：99.06000
LogP:0.08580
XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:183.06439116
Heavy Atom Count:13
Complexity:188

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=NC(=NC=C1C(=O)O)N

Technology Process of 2-Amino-4-ethoxypyrimidine-5-carboxylic acid

There total 4 articles about 2-Amino-4-ethoxypyrimidine-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 72419-38-6
2-Amino-4-ethoxy-pyrimidine-5-carboxylic acid ethyl ester

: 72411-91-7
2-amino-4-ethoxy-5-pyrimidinyl carboxylic acid

Guidance literature:: With sodium hydroxide; In methanol; water; at 65 ℃; for 1h; Yield given;

Reference yield:

: 15400-53-0
ethyl 2-amino-4-hydroxypyrimidine-5-carboxylate

: 72411-91-7
2-amino-4-ethoxy-5-pyrimidinyl carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 62 percent / pyridine / 2 h / Heating

2: 81 percent / phosphorus oxychloride / 2 h / 60 °C

3: 93 percent / sodium / Ambient temperature

4: NaOH / methanol; H₂O / 1 h / 65 °C

With sodium hydroxide; sodium; trichlorophosphate; In pyridine; methanol; water;

Reference yield:

: 344311-74-6
2-Acetylamino-4-hydroxy-pyrimidine-5-carboxylic acid ethyl ester

: 72411-91-7
2-amino-4-ethoxy-5-pyrimidinyl carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 81 percent / phosphorus oxychloride / 2 h / 60 °C

2: 93 percent / sodium / Ambient temperature

3: NaOH / methanol; H₂O / 1 h / 65 °C

With sodium hydroxide; sodium; trichlorophosphate; In methanol; water;